Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.46 |
| ▸ | MMP2 | P08253 | 6/20 | 0.46 |
| ▸ | MMP9 | P14780 | 6/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682528 | 0.80 | CYP19A1 (0.48) | CYP19A1NR3C1MMP2MMP9NR3C2 | |
| SCHEMBL27682527 | 0.80 | CYP19A1 (0.48) | CYP19A1NR3C1MMP2MMP9NR3C2 | |
| SCHEMBL27701618 | 0.80 | CYP19A1 (0.48) | CYP19A1NR3C1MMP2MMP9NR3C2 | |
| SCHEMBL10396392 | 0.78 | GPR84 (0.45) | CYP19A1NR3C1NR3C2PGRMEN1 | |
| SCHEMBL949157 | 0.76 | GPR84 (0.49) | CYP19A1MMP2MMP9MEN1MAPT | |
| SCHEMBL27682596 | 0.74 | MMP9 (0.44) | CYP19A1NR3C1MMP2MMP9NR3C2 | |
| SCHEMBL27682594 | 0.74 | MMP9 (0.44) | CYP19A1NR3C1MMP2MMP9NR3C2 | |
| SCHEMBL16774550 | 0.72 | NR3C1 (0.58) | CYP19A1NR3C1MMP2MMP9NR3C2 | |
| SCHEMBL27760366 | 0.72 | NR3C1 (0.58) | CYP19A1NR3C1MMP2MMP9NR3C2 | |
| SCHEMBL16774548 | 0.72 | NR3C1 (0.58) | CYP19A1NR3C1MMP2MMP9NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8157471-A | — | — | None | — | — | JP | disclosed |
| JP-H08157471-A | 3-(BENZENESULFONAMIDOALKYL)INDOLE DERIVATIVE | TERUMO CORP | 1996-06-18 | — | — | JP | disclosed |