SCHEMBL9064170

SCHEMBL9064170

COC(=O)C1(C(=O)OC)CCC(C=O)CC1

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.34
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064174 0.91 LMNA (0.32) NPSR1MAPTLMNA
SCHEMBL20295889 0.82 FFAR3 (0.33) NPSR1MAPTLMNA
SCHEMBL26649087 0.81 NPSR1 (0.32) NPSR1MAPT
SCHEMBL4870839 0.77 NPSR1 (0.38) NPSR1MAPTLMNA
SCHEMBL9550343 0.77 NPSR1 (0.38) NPSR1MAPTLMNA
SCHEMBL14394093 0.75 CYP4F2 (0.41) MAPT
SCHEMBL14128933 0.75 EPHX2 (0.37) NPSR1MAPTLMNA
SCHEMBL225044 0.75 NPSR1 (0.46) NPSR1MAPTLMNA
SCHEMBL12462298 0.75 NPSR1 (0.46) NPSR1MAPTLMNA
SCHEMBL12462745 0.73 LMNA (0.38) NPSR1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553322-A1 RECOVERY OF HIGH-BOILING ALDEHYDES FROM RHODIUM-CATALYZED HYDROFORMYLATION PROCESSES. EASTMAN KODAK CO (US) 1993-08-04 EP claimed
WO-1993002024-A2 RECOVERY OF HIGH-BOILING ALDEHYDES FROM RHODIUM-CATALYZED HYDROFORMYLATION PROCESSES EASTMAN KODAK COMPANY (US) 1993-02-04 WO claimed
US-5138101-A Solvent extraction using alcohol and water EASTMAN KODAK COMPANY (US) 1992-08-11 US claimed
US-20120298916-A1 POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-11-29 US disclosed
WO-2011088882-A1 POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA MERCK PATENT GMBH (DE) 2011-07-28 WO disclosed
EP-0553322-B1 RECOVERY OF HIGH-BOILING ALDEHYDES FROM RHODIUM-CATALYZED HYDROFORMYLATION PROCESSES EASTMAN CHEM CO (US) 1996-05-29 EP disclosed
EP-0553322-A1 RECOVERY OF HIGH-BOILING ALDEHYDES FROM RHODIUM-CATALYZED HYDROFORMYLATION PROCESSES. EASTMAN KODAK CO (US) 1993-08-04 EP disclosed
WO-1993002024-A2 RECOVERY OF HIGH-BOILING ALDEHYDES FROM RHODIUM-CATALYZED HYDROFORMYLATION PROCESSES EASTMAN KODAK COMPANY (US) 1993-02-04 WO disclosed
US-5138101-A Solvent extraction using alcohol and water EASTMAN KODAK COMPANY (US) 1992-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120298916-A1 POLYMERIZABLE COMPOUNDS AND LIQUID CRYSTAL MEDIA RCC1, CCNB2, CCNB1 NPSR1 3771/4885MAPT 101/4885LMNA 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.