Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612246 | 0.83 | OPRK1 (0.51) | OPRK1DRD2DRD1TAAR1OPRM1 | |
| 3-Phenethylphenol SCHEMBL717571 | 0.81 | OPRK1 (0.74) | OPRK1DRD2NR1H3DRD1TAAR1 | |
| SCHEMBL27685427 | 0.79 | BCL2 (0.45) | OPRK1DRD2DRD1OPRM1OPRD1 | |
| SCHEMBL723832 | 0.79 | DRD2 (0.74) | OPRK1DRD2DRD1TAAR1OPRM1 | |
| SCHEMBL30482909 | 0.78 | F2 (0.58) | OPRK1DRD2BACE1NR1H3DRD1 | |
| SCHEMBL21612701 | 0.77 | BACE1 (0.74) | OPRK1BACE1NR1H3DRD1ALOX5 | |
| SCHEMBL27685495 | 0.76 | CYP17A1 (0.43) | ALOX5ESR2 | |
| SCHEMBL28238086 | 0.76 | PTPN1 (0.50) | BACE1ALOX5ESR2 | |
| SCHEMBL8956610 | 0.76 | BACE1 (0.79) | BACE1ALOX5 | |
| SCHEMBL8450704 | 0.76 | ALOX5 (0.63) | BACE1ALOX5ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8333287-A | — | — | None | — | — | JP | disclosed |
| JP-H08333287-A | AROMATIC RING-SUBSTITUTED ALKYLCARBOXYLIC ACID AND ALKANOL DERIVATIVE AND ANTITHROMBOGENIC MEDICINE CONTAINING THESE COMPOUNDS | FUJI YAKUHIN KOGYO KK | 1996-12-17 | — | — | JP | disclosed |