Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064599 | 0.89 | THRB (0.41) | THRBTHRAHCRTR1KCNK3KCNK9 | |
| SCHEMBL228775 | 0.88 | THRB (0.39) | THRBTHRAHCRTR1L3MBTL1ALDH1A1 | |
| SCHEMBL29385502 | 0.88 | THRB (0.39) | THRBTHRAHCRTR1L3MBTL1ALDH1A1 | |
| SCHEMBL28931543 | 0.87 | THRB (0.51) | THRBTHRAHCRTR1L3MBTL1GLA | |
| SCHEMBL9065256 | 0.85 | THRB (0.38) | THRBTHRATYMSMAPTTDP1 | |
| SCHEMBL29636328 | 0.84 | THRB (0.49) | THRBTHRAHCRTR1L3MBTL1GLA | |
| SCHEMBL28085570 | 0.84 | THRB (0.49) | THRBTHRAHCRTR1L3MBTL1GLA | |
| Propane SCHEMBL27699149 | 0.83 | THRB (0.48) | THRBTHRAHCRTR1L3MBTL1GLA | |
| Phenol SCHEMBL5441534 | 0.83 | THRB (0.39) | THRBTHRAHCRTR1L3MBTL1GLA | |
| SCHEMBL9064851 | 0.82 | ATM (0.40) | HCRTR1KCNK3KCNK9L3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540003-B1 | Cast resin for optical use | NOF CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5336743-A | Diallylphthalate component and an alkylene bis-allylcarbonate component | NOF CORPORATION (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0540003-A1 | Cast resin for optical use | NOF CORPORATION (JP) | 1993-05-05 | — | — | EP | disclosed |