Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785859 | 0.86 | THRB (0.36) | THRBTHRATYMS | |
| SCHEMBL11212312 | 0.85 | THRB (0.34) | THRBTHRATSHR | |
| SCHEMBL9064604 | 0.85 | THRB (0.44) | THRBTHRATYMSMAPTATM | |
| SCHEMBL8979696 | 0.84 | ATM (0.36) | LMNATSHRMAPTATMTDP1 | |
| SCHEMBL27888638 | 0.84 | THRB (0.38) | THRBTHRATSHRATMTDP1 | |
| SCHEMBL869200 | 0.81 | LMNA (0.34) | LMNAMAPTPTPN1 | |
| SCHEMBL28889861 | 0.80 | THRB (0.40) | THRBTHRALMNAADRB2ADRB1 | |
| SCHEMBL9064599 | 0.77 | THRB (0.41) | THRBTHRAMAPTCYP1A2 | |
| SCHEMBL6054116 | 0.77 | THRB (0.39) | THRBTHRALMNAADRB2ADRB1 | |
| SCHEMBL1833758 | 0.75 | THRB (0.49) | THRBTHRATYMSMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567349-A | Photo cross-linkable liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0540003-B1 | Cast resin for optical use | NOF CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5336743-A | Diallylphthalate component and an alkylene bis-allylcarbonate component | NOF CORPORATION (JP) | 1994-08-09 | — | — | US | disclosed |
| EP-0540003-A1 | Cast resin for optical use | NOF CORPORATION (JP) | 1993-05-05 | — | — | EP | disclosed |