SCHEMBL9064663

SCHEMBL9064663

O=C(O)C(Cc1ccc(Cl)cc1)=C(Cc1ccc(Cl)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTBP2 P56545 1/20 0.60
L3MBTL1 Q9Y468 3/20 0.52
MAPT P10636 2/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
PIK3CA P42336 2/20 0.47
CNR2 P34972 1/20 0.47
CYP3A4 P08684 1/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
EGFR P00533 2/20 0.46
ERBB2 P04626 2/20 0.46
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065171 1.00 CTBP2 (0.60) CTBP2L3MBTL1MAPTNPC1RAB9A
SCHEMBL9064655 1.00 CTBP2 (0.60) CTBP2L3MBTL1MAPTNPC1RAB9A
SCHEMBL2456763 0.82 CTBP2 (0.60) CTBP2L3MBTL1MAPTNPC1RAB9A
SCHEMBL75665 0.81 CA2 (0.62) CTBP2L3MBTL1MAPTNPC1RAB9A
Methane SCHEMBL1994900 0.79 CA2 (0.60) CTBP2L3MBTL1MAPTNPC1RAB9A
Hydrochloric Acid SCHEMBL76051 0.79 CA2 (0.60) CTBP2L3MBTL1MAPTNPC1RAB9A
SCHEMBL48823 0.79 L3MBTL1 (0.55) CTBP2L3MBTL1MAPTNPC1RAB9A
SCHEMBL28038880 0.79 CA2 (0.60) CTBP2L3MBTL1MAPTNPC1RAB9A
SCHEMBL1629363 0.78 CTBP2 (0.56) CTBP2L3MBTL1MAPTNPC1RAB9A
SCHEMBL1479915 0.78 NPC1 (0.55) CTBP2L3MBTL1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0540003-B1 Cast resin for optical use NOF CORP (JP) 1996-05-08 EP disclosed
US-5336743-A Diallylphthalate component and an alkylene bis-allylcarbonate component NOF CORPORATION (JP) 1994-08-09 US disclosed
EP-0540003-A1 Cast resin for optical use NOF CORPORATION (JP) 1993-05-05 EP disclosed
EP-0031997-B2 POLYMERISATION PROCESS FOR PRODUCTION OF POLYMER MICROPARTICLES OF HIGH REFRACTIVE INDEX AND COATING COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-09-14 EP disclosed
US-4427820-A STYRENE, MALEIC ACID DERIVATIVE, EMULSION POLYMERIZATION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-24 US disclosed
EP-0031997-B1 POLYMERISATION PROCESS FOR PRODUCTION OF POLYMER MICROPARTICLES OF HIGH REFRACTIVE INDEX AND COATING COMPOSITIONS CONTAINING THEM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-28 EP disclosed
EP-0031997-A1 Polymerisation process for production of polymer microparticles of high refractive index and coating compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-07-15 EP disclosed