Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.60 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | C1S | P09871 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.53 |
| ▸ | FEN1 | P39748 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064663 | 0.82 | CTBP2 (0.60) | CTBP2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL9065171 | 0.82 | CTBP2 (0.60) | CTBP2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL9064655 | 0.82 | CTBP2 (0.60) | CTBP2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL75665 | 0.81 | CA2 (0.62) | CTBP2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL4644802 | 0.80 | EGFR (0.49) | CTBP2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL1512090 | 0.80 | CYP2C9 (0.52) | CTBP2L3MBTL1MAPTNPC1RAB9A | |
| SCHEMBL4647085 | 0.80 | LMNA (0.52) | CTBP2L3MBTL1MAPTNPC1RAB9A | |
| 4-Hydroxyphenylpyruvic Acid SCHEMBL24157 | 0.79 | FNTA (0.72) | CTBP2F2PLGPRSS1PRSS2 | |
| SCHEMBL17707273 | 0.79 | CA1 (0.54) | CTBP2L3MBTL1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL76051 | 0.79 | CA2 (0.60) | CTBP2L3MBTL1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550277-B2 | D-amino acid dehydrogenase and method of making D-amino acids | CODEXIS, INC. (US) | 2009-06-23 | — | — | US | claimed |
| US-20080182972-A1 | D-amino acid dehydrogenase and method of making D-amino acids | INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT | 2008-07-31 | — | — | US | claimed |
| EP-1896574-A2 | D-AMINO ACID DEHYDROGENASE AND METHOD OF MAKING D-AMINO ACIDS | BioCatalytics Inc. (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2006113085-A2 | D-AMINO ACID DEHYDROGENASE AND METHOD OF MAKING D-AMINO ACIDS | BIOCATALYTICS, INC. (US) | 2006-10-26 | — | — | WO | claimed |
| US-4481368-A | Process for preparing α-keto-carboxylic acids from acyl halides | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | claimed |
| US-4481369-A | VIA TRICARBONYL(TRIPHENYLPOSPHINE) COBALTATE | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | claimed |
| CN-121718517-A | D-amino acid transaminase mutant and method for preparing 4-chloro-D-phenylalanine | 上海合全药业股份有限公司 | 2026-03-24 | — | — | CN | disclosed |
| WO-2024251301-A1 | GSPT1 PROTEIN DEGRADER CONTAINING OXIME STRUCTURE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国药科大学 | 2024-12-12 | — | — | WO | disclosed |
| CN-119080738-A | GSPT1 protein degradation agent containing oxime structure and preparation method and application thereof | 中国药科大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-112142587-B | Acetophenone acid and preparation method and application thereof | 长沙嘉桥生物科技有限公司 | 2023-05-12 | — | — | CN | disclosed |
| WO-2023031246-A1 | SUBSTITUTED THIOPHENE COMPOUNDS AS D-DOPACHROME TAUTOMERASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2023-03-09 | — | — | WO | disclosed |
| US-10174065-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | ZADEC APS (DK) | 2019-01-08 | — | — | US | disclosed |
| EP-2514739-B1 | Substituted beta-phenyl-alpha-hydroxy propanoic acid, synthesis method and use thereof | UNIV NORTHWEST (CN) | 2016-12-21 | — | — | EP | disclosed |
| US-4849345-A | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-07-18 | — | — | US | disclosed |
| EP-0206460-A2 | L-phenylalanine dehydrogenase and use thereof | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4481369-A | VIA TRICARBONYL(TRIPHENYLPOSPHINE) COBALTATE | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4481368-A | Process for preparing α-keto-carboxylic acids from acyl halides | ETHYL CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4447644-A | Method for preparation of arylpyruvic acid | DYNAMIT NOBEL AG (DE) | 1984-05-08 | — | — | US | disclosed |
| US-4369206-A | HARDENING COATING WITH AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-01-18 | — | — | US | disclosed |
| US-4152352-A | PRODUCTION OF ARYLPYRUVIC ACIDS | RHONE-POULENC INDUSTRIES (FR) | 1979-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174065-B2 | Antidiabetic enolic glucoside of phenylpyruvic acid | PC, SLC5A1, SLC5A2 | CTBP2 2912/4885F2 2179/4885PLG 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.