SCHEMBL906482

SCHEMBL906482

COc1ccc(C(=O)C(=O)O)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.78
CES1 P23141 2/20 0.78
CA1 P00915 6/20 0.68
CA2 P00918 6/20 0.68
MAPT P10636 2/20 0.64
PARP10 Q53GL7 2/20 0.59
PARP1 P09874 1/20 0.59
PARP2 Q9UGN5 1/20 0.59
PARP4 Q9UKK3 1/20 0.59
PLK1 P53350 1/20 0.55
PTPRC P08575 1/20 0.55
PTPN2 P17706 1/20 0.55
PTPN1 P18031 1/20 0.55
CPT1B Q92523 1/20 0.54
GSK3B P49841 1/20 0.53
MEN1 O00255 1/20 0.53
LMNA P02545 1/20 0.53
MAPK1 P28482 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9044800 0.89 CES2 (0.62) CES2CES1CA1CA2MAPT
SCHEMBL557152 0.88 CES2 (1.00) CES2CES1CA1CA2MAPT
SCHEMBL14507040 0.88 CES2 (1.00) CES2CES1CA1CA2MAPT
SCHEMBL3757289 0.87 CES2 (0.72) CES2CES1CA1CA2MAPT
SCHEMBL29548151 0.86 CES2 (0.95) CES2CES1CA1CA2MAPT
SCHEMBL2156563 0.84 CES2 (1.00) CES2CES1CA1CA2MAPT
SCHEMBL28140959 0.84 CES2 (0.82) CES2CES1CA1CA2MAPT
SCHEMBL15392261 0.84 MAPT (0.67) CES2CES1CA1CA2MAPT
Hydrochloric Acid SCHEMBL905770 0.83 CES2 (0.96) CES2CES1CA1CA2MAPT
Bromide SCHEMBL981452 0.83 CES2 (0.96) CES2CES1CA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752955-B Method for electrochemically synthesizing N-nitroso-2-aminobenzophenone compound 广西师范大学 2023-06-16 CN claimed
CN-111978201-B Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2023-01-03 CN claimed
CN-111978201-A Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2020-11-24 CN claimed
CN-111100085-A Preparation method of 3-aryl-2H-benzo [ β ] [1,4] benzoxazine-2-one compound 东华理工大学 2020-05-05 CN claimed
CN-111056890-A Method for preparing aryl ketone by free radical-free radical coupling reaction of ketoacid decarboxylation and fatty aldehyde decarbonylation based on iron catalysis 湘潭大学 2020-04-24 CN claimed
CN-109503597-A The method of level-one amine guiding building 6- (4- methoxyphenyl) indoles simultaneously [1,2-a] quinoxaline 桂林理工大学 2019-03-22 CN claimed
EP-0975584-B1 SYNTHESIS AND USE OF ALPHA-KETOAMIDE DERIVATIVES AND ARRAYS ARQULE INC (US) 2002-09-25 EP claimed
WO-2000038632-A1 METHOD FOR DYING KERATIN FIBERS USING 2-OXOCARBOXYLIC ACID DERIVATIVES IN CONJUNCTION WITH NUCLEOPHILES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 WO claimed
WO-2026100697-A1 PHOTOCURABLE EPISULFIDE COMPOSITION, CURED PRODUCT, LAMINATE, AND METHOD FOR PRODUCING CURED PRODUCT 三井化学株式会社 2026-05-15 WO disclosed
WO-2025056724-A1 IMINOAMIDE-TYPE COMPOUNDS AS LIGANDS FOR COPPER-CATALYZED COUPLING REACTIONS OF (HETERO)ARYL HALIDES BAYER AKTIENGESELLSCHAFT (DE) 2025-03-20 WO disclosed
CN-110218178-B Synthesis method of optical active succinate derivative containing pyridyl substituent 中山大学 2023-06-30 CN disclosed
CN-114752955-B Method for electrochemically synthesizing N-nitroso-2-aminobenzophenone compound 广西师范大学 2023-06-16 CN disclosed
CN-115677443-A Method for constructing 1, 4-diketone compound by olefin 1, 2-dicarbonylation 中国科学院理化技术研究所 2023-02-03 CN disclosed
CN-111978201-B Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2023-01-03 CN disclosed
US-4239779-A AND AS A HYPOGLYCEMIC AGENT PFIZER INC. (US) 1980-12-16 US disclosed
US-4219566-A TREATMENT OF ISCHEMIC HEART DISEASE AND HYPERGLYCEMIA OF DIABETES PFIZER INC. (US) 1980-08-26 US disclosed
US-4207234-A 4-Unsubstituted azetidinone derivatives and process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-06-10 US disclosed
EP-0008626-A1 Ammonium salts of alpha-ketocarboxylic acids, their use in the preparation of amines and coating materials containing them BAYER AG (DE) 1980-03-19 EP disclosed
US-4181800-A ANTIBIOTICS FROM SUBSTITUTED PERHYDRO-S-TRIAZINES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-01-01 US disclosed
US-4038253-A PHOTOCROSS-LINKABLE POLYMERS CONTAINING PENDANT DIAZOESTER GROUPS HERCULES INCORPORATED (US) 1977-07-26 US disclosed