Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94147 | 0.90 | MGLL (0.46) | MGLLFAAHNPSR1MEN1KMT2A | |
| SCHEMBL9471176 | 0.86 | FAAH (0.41) | MGLLFAAHPOLBHPGDNPSR1 | |
| SCHEMBL8142750 | 0.84 | MGLL (0.57) | MGLLHSD17B10MEN1KMT2ARAB9A | |
| SCHEMBL4839640 | 0.82 | MGLL (0.61) | MGLLFAAHHPGDNPSR1MAPK1 | |
| SCHEMBL10704906 | 0.81 | MEN1 (0.56) | MGLLPOLBHPGDNPSR1MEN1 | |
| SCHEMBL8443563 | 0.81 | MGLL (0.53) | MGLLFAAHPOLBNPSR1MEN1 | |
| SCHEMBL8885247 | 0.81 | CCR6 (0.35) | MGLLFAAHPOLBNPSR1HSD17B10 | |
| SCHEMBL774452 | 0.80 | MGLL (0.50) | MGLLFAAHNPSR1MEN1KMT2A | |
| SCHEMBL9198677 | 0.79 | MGLL (0.38) | MGLLFAAHHSD17B10MEN1KMT2A | |
| SCHEMBL13632610 | 0.79 | ALDH1A1 (0.42) | MGLLFAAHHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111316986-B | Application of maleimide compound as chitin synthetase inhibitor | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-111316986-A | Application of maleimide compound as chitin synthetase inhibitor | 浙江工业大学 | 2020-06-23 | — | — | CN | disclosed |
| US-5523360-A | IMPROVES MELT-FLOW PROPERTIES | AKZO NOBEL N. V. (NL) | 1996-06-04 | — | — | US | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| EP-0495545-B1 | Citraconimide (co)polymers and curing with anionic catalyst | AKZO NOBEL NV (NL) | 1994-12-28 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |
| US-5221717-A | CITRACONIMIDE (CO)POLYMERS AND CURING WITH ANIONIC CATALYST | AKZO N.V. (NL) | 1993-06-22 | — | — | US | disclosed |
| EP-0495545-A1 | Citraconimide (co)polymers and curing with anionic catalyst | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |
| EP-0188904-B1 | FLAME RETARDANT MOLDED COMPOSITION INCORPORATING A POLY (N-(BROMOPHENYL) MALEIMIDE-CO-STYRENE-CO-MALEIC ANHYDRIDE) COPOLYMER | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1989-07-26 | — | — | EP | disclosed |
| EP-0190507-B1 | FLAME RETARDANT MOLDED COMPOSITION WHICH INCORPORATES A POLY (N-(BROMOPHENYL) MALEIMIDE-CO-STYRENE-CO-N-PHENYLMALEIMIDE)) COPOLYMER | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4661574-A | SYNERGISTIC | ATLANTIC RICHFIELD COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| US-4626573-A | Flame-retardant molded composition incorporating a poly(N-(bromophenyl)maleimide-co-styrene-co-maleic anhydride) copolymer | ATLANTIC RICHFIELD COMPANY (US) | 1986-12-02 | — | — | US | disclosed |
| US-4609711-A | AND SYNERGIST | ATLANTIC RICHFIELD COMPANY (US) | 1986-09-02 | — | — | US | disclosed |
| EP-0190507-A1 | Flame retardant molded composition which incorporates a poly (N-(bromophenyl) maleimide-co-styrene-co-N-phenylmaleimide)) copolymer | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1986-08-13 | — | — | EP | disclosed |
| US-4604422-A | POLYCARBONATES AND ANTIMONY TRIOXIDE | ATLANTIC RICHFIELD COMPANY (US) | 1986-08-05 | — | — | US | disclosed |
| EP-0188904-A1 | Flame retardant molded composition incorporating a poly (N-(bromophenyl) maleimide-co-styrene-co-maleic anhydride) copolymer | ARCO CHEMICAL TECHNOLOGY, INC. (US) | 1986-07-30 | — | — | EP | disclosed |