Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 5/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94147 | 0.90 | MGLL (0.46) | MGLLHSP90AA1PKMMAPK1NPSR1 | |
| SCHEMBL8142750 | 0.84 | MGLL (0.57) | MGLLMAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL4839640 | 0.82 | MGLL (0.61) | MGLLHSP90AA1PKMMAPK1NPSR1 | |
| SCHEMBL8884854 | 0.81 | CCR6 (0.35) | MGLLHSP90AA1PKMMAPK1NPSR1 | |
| SCHEMBL9065005 | 0.81 | MGLL (0.53) | MGLLHSP90AA1MAPK1NPSR1POLB | |
| SCHEMBL28434063 | 0.81 | MGLL (0.53) | MGLLPOLBKMT2AMEN1KDM4E | |
| SCHEMBL26659413 | 0.81 | ALDH1A1 (0.46) | MGLLMAPK1NPSR1ESR2KMT2A | |
| SCHEMBL10704906 | 0.81 | MEN1 (0.56) | MGLLNPSR1POLBKMT2AMEN1 | |
| SCHEMBL8442000 | 0.80 | DDAH1 (0.58) | NPSR1TDP1POLBKMT2AMEN1 | |
| SCHEMBL9064941 | 0.80 | KMT2A (0.46) | HSP90AA1NPSR1TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111316986-B | Application of maleimide compound as chitin synthetase inhibitor | 浙江工业大学 | 2021-10-15 | — | — | CN | disclosed |
| CN-111316986-A | Application of maleimide compound as chitin synthetase inhibitor | 浙江工业大学 | 2020-06-23 | — | — | CN | disclosed |
| CN-107162950-A | N substitution maleimide compounds and its preparation based on pharmaceutical intermediate are studied with antibacterial activity | 浙江工业大学 | 2017-09-15 | — | — | CN | disclosed |
| EP-0495544-B1 | Process for the synthesis of citraconimides | AKZO NOBEL NV (NL) | 1999-04-07 | — | — | EP | disclosed |
| US-5523360-A | IMPROVES MELT-FLOW PROPERTIES | AKZO NOBEL N. V. (NL) | 1996-06-04 | — | — | US | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| EP-0495545-B1 | Citraconimide (co)polymers and curing with anionic catalyst | AKZO NOBEL NV (NL) | 1994-12-28 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |
| US-5221717-A | CITRACONIMIDE (CO)POLYMERS AND CURING WITH ANIONIC CATALYST | AKZO N.V. (NL) | 1993-06-22 | — | — | US | disclosed |
| EP-0495545-A1 | Citraconimide (co)polymers and curing with anionic catalyst | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |