Pyridine

Pyridine

SCHEMBL9065176

O=C1CCC(=O)N1OS(=O)(=O)O.c1ccncc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PARL Q9H300 4/20 0.50
NAPRT Q6XQN6 2/20 0.34
ALOX12 P18054 1/20 0.32
ALDH1A1 P00352 3/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KDM4E B2RXH2 2/20 0.31
HPGD P15428 2/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
GRIN1 Q05586 1/20 0.30
GRIN2B Q13224 1/20 0.30
MMP2 P08253 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702307 0.83 PARL (0.50) PARL
SCHEMBL28981837 0.81 PARL (0.48) PARL
Pyridine SCHEMBL3849496 0.75 PARL (0.37) PARLNAPRTALOX12ALDH1A1TSHR
Benzene SCHEMBL28164184 0.70 PARL (0.60) PARLALOX12ALDH1A1SMN1; SMN2KDM4E
SCHEMBL9064898 0.69 PARL (0.34) PARL
Pyridine SCHEMBL2255454 0.68 NAPRT (0.47) NAPRTTSHRTDP1MAPTKMT2A
Pyridine SCHEMBL28257184 0.68 CA2 (0.53) NAPRTTSHRTDP1MAPTKMT2A
Pyridine SCHEMBL2424842 0.68 CA2 (0.53) NAPRTTSHRTDP1MAPTKMT2A
Pyridine SCHEMBL9785253 0.68 NAPRT (0.47) NAPRTTSHRTDP1MAPTKMT2A
Pyridine SCHEMBL984983 0.68 TSHR (0.53) NAPRTALDH1A1SMN1; SMN2TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5366591-A Cyclic N-sulfatoimide WEYERHAEUSER 1994-11-22 US claimed
WO-1993014261-A1 METHOD FOR CROSSLINKING INDIVIDUALIZED CELLULOSE FIBRES WEYERHAEUSER COMPANY (US) 1993-07-22 WO claimed
US-5556976-A FORMING WET AND DRY RESILIENT CELLULOSE FIBERS WITH HIGH ABSORBENCY, BULK AND WET AND DRY RESILIENCY FOR PAPER TOWELS, DIAPERS AND SANITARY PRODUCTS JEWELL RICHARD A (US) 1996-09-17 US disclosed
US-5556976-A FORMING WET AND DRY RESILIENT CELLULOSE FIBERS WITH HIGH ABSORBENCY, BULK AND WET AND DRY RESILIENCY FOR PAPER TOWELS, DIAPERS AND SANITARY PRODUCTS JEWELL RICHARD A (US) 1996-09-17 US disclosed
US-5366591-A Cyclic N-sulfatoimide WEYERHAEUSER 1994-11-22 US disclosed
US-5366591-A Cyclic N-sulfatoimide WEYERHAEUSER 1994-11-22 US disclosed
WO-1993014261-A1 METHOD FOR CROSSLINKING INDIVIDUALIZED CELLULOSE FIBRES WEYERHAEUSER COMPANY (US) 1993-07-22 WO disclosed
WO-1993014261-A1 METHOD FOR CROSSLINKING INDIVIDUALIZED CELLULOSE FIBRES WEYERHAEUSER COMPANY (US) 1993-07-22 WO disclosed