Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARL | Q9H300 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28277653 | 0.82 | MGLL (0.36) | PARLMGLLKMT2AALOX12CA12 | |
| Pyridine SCHEMBL28214805 | 0.78 | ALDH1A1 (0.33) | PARLMGLLKMT2AMEN1ALOX12 | |
| SCHEMBL28071232 | 0.78 | MGLL (0.35) | PARLMGLL | |
| 2-Aminopyridine SCHEMBL1205100 | 0.77 | NOS3 (0.48) | PARLMGLLKMT2AMEN1ALOX12 | |
| SCHEMBL2581766 | 0.76 | KMT2A (0.43) | KMT2AMEN1TSHRTDP1ALDH1A1 | |
| Pyridine SCHEMBL9065176 | 0.75 | PARL (0.50) | PARLKMT2AALOX12TSHRNAPRT | |
| SCHEMBL19928412 | 0.75 | MGLL (0.35) | PARLMGLL | |
| Ethylene Glycol SCHEMBL8522385 | 0.74 | MGLL (0.33) | PARLMGLLALOX12 | |
| SCHEMBL1491245 | 0.74 | CYP19A1 (0.43) | KMT2AMEN1TSHRALDH1A1CCNE1 | |
| SCHEMBL2139612 | 0.73 | MGLL (0.35) | PARLMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102271712-B | For by substance delivery to the compositions of biological target and method | THE GENERAL HOSPITAL CORP. (US) | 2015-11-25 | — | — | CN | disclosed |
| EP-2035505-A1 | OPTICAL FLUORESCENT IMAGING USING CYANINE DYES | LI-COR, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007136996-A1 | OPTICAL FLUORESCENT IMAGING USING CYANINE DYES | LI-COR, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| EP-1319047-A1 | CYANINE DYES | Li-Cor, Inc. (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024815-A1 | CYANINE DYES | LI-COR, INC. (US) | 2002-03-28 | — | — | WO | disclosed |