Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.49 |
| ▸ | KYNU | Q16719 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5729277 | 1.00 | KIF11 (0.49) | KIF11KYNUPOLBALPIPKM | |
| SCHEMBL6223407 | 0.79 | MAOA (0.57) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL1157625 | 0.79 | MAOA (0.57) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL342512 | 0.79 | MAOA (0.57) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL25766501 | 0.79 | KIF11 (0.46) | KIF11POLBDNMT1 | |
| SCHEMBL29180223 | 0.78 | CPA3 (0.49) | POLBHSD17B10 | |
| SCHEMBL759475 | 0.78 | CPA1 (0.49) | POLBHSD17B10 | |
| SCHEMBL7819718 | 0.78 | MAOA (0.55) | KIF11ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL3319856 | 0.78 | MAOA (0.55) | KIF11ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL10981166 | 0.78 | MAOA (0.55) | KIF11ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976781-A | SULFUR CONTAINING AMINES | L'OREAL (FR) | 1976-08-24 | — | — | US | claimed |
| CN-117551707-A | Preparation method of S-substituted cysteine, AMA derivative and preparation method thereof | 中国药科大学 | 2024-02-13 | — | — | CN | disclosed |
| US-5516936-A | TREATMENT OF NEUROLOGICAL DISORDERS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5442104-A | Neurological disorders | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0581907-A4 | — | — | 1994-04-06 | — | — | EP | disclosed |
| EP-0581907-A1 | INHIBITORS OF KYNURENINASE | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992018003-A1 | INHIBITORS OF KYNURENINASE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-10-29 | — | — | WO | disclosed |