Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.49 |
| ▸ | KYNU | Q16719 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065198 | 1.00 | KIF11 (0.49) | KIF11KYNUPOLBALPIPKM | |
| SCHEMBL6223407 | 0.79 | MAOA (0.57) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL1157625 | 0.79 | MAOA (0.57) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL342512 | 0.79 | MAOA (0.57) | KIF11ALPIPKMPTGS1XIAP | |
| SCHEMBL25766501 | 0.79 | KIF11 (0.46) | KIF11POLBDNMT1 | |
| SCHEMBL29180223 | 0.78 | CPA3 (0.49) | POLBHSD17B10 | |
| SCHEMBL759475 | 0.78 | CPA1 (0.49) | POLBHSD17B10 | |
| SCHEMBL7819718 | 0.78 | MAOA (0.55) | KIF11ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL3319856 | 0.78 | MAOA (0.55) | KIF11ALPIPKMPTGS1XIAP | |
| Hydrochloric Acid SCHEMBL10981166 | 0.78 | MAOA (0.55) | KIF11ALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976781-A | SULFUR CONTAINING AMINES | L'OREAL (FR) | 1976-08-24 | — | — | US | claimed |
| CN-117551707-A | Preparation method of S-substituted cysteine, AMA derivative and preparation method thereof | 中国药科大学 | 2024-02-13 | — | — | CN | disclosed |
| EP-3067430-B1 | METHOD FOR PRODUCING D-FORM OR L-FORM AMINO ACID DERIVATIVE HAVING THIOL GROUP | GLYTECH INC (JP) | 2020-08-12 | — | — | EP | disclosed |
| WO-2019006384-A1 | TREATMENT OF ANEURYSMS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-01-03 | — | — | WO | disclosed |
| CN-100413972-C | Enzymatic process for preparing substituted 2-amino-3- (2-amino-thiophenyl) -propionic acids | HOFFMANN LA ROCHE (CH) | 2008-08-27 | — | — | CN | disclosed |
| EP-1434870-B1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | HOFFMANN LA ROCHE (CH) | 2006-12-27 | — | — | EP | disclosed |
| EP-1434870-B1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | HOFFMANN LA ROCHE (CH) | 2006-12-27 | — | — | EP | disclosed |
| US-7011960-B2 | Substituted 2-amino-3-(2-amino-phenylsulfanyl)-propionic acids | HOFFMANN-LA ROCHE INC. (US) | 2006-03-14 | — | — | US | disclosed |
| US-7011960-B2 | Substituted 2-amino-3-(2-amino-phenylsulfanyl)-propionic acids | HOFFMANN-LA ROCHE INC. (US) | 2006-03-14 | — | — | US | disclosed |
| CN-1553959-A | Enzymatic process for preparing substituted 2-amino-3- (2-amino-thiophenyl) -propionic acids | - | 2004-12-08 | — | — | CN | disclosed |
| EP-1434870-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-07 | — | — | EP | disclosed |
| EP-1434870-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2004-07-07 | — | — | EP | disclosed |
| US-20030119152-A1 | Substituted 2-amino-3- (2-amino-phenylsulfanyl) -propionic acids | HOFFMANN-LA ROCHE INC. | 2003-06-26 | — | — | US | disclosed |
| US-20030119152-A1 | Substituted 2-amino-3- (2-amino-phenylsulfanyl) -propionic acids | HOFFMANN-LA ROCHE INC. | 2003-06-26 | — | — | US | disclosed |
| WO-2003029477-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | WO | disclosed |
| WO-2003029477-A1 | ENZYMATIC PROCESS FOR THE PREPARATION OF SUBSTITUTED 2-AMINO-3-(2-AMINO-PHENYLSULFANYL)-PROPIONIC ACID | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030119152-A1 | Substituted 2-amino-3- (2-amino-phenylsulfanyl) -propionic acids | CCKAR, AGTR1, AGTR2 | KIF11 3516/4885KYNU 531/4885POLB 3553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.