Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996063 | 0.92 | KDM4E (0.47) | KDM4EALOX5STAT3NFE2L2PTGS1 | |
| SCHEMBL1515768 | 0.87 | KDM4E (0.61) | KDM4EALOX5STAT3NFE2L2PTGS1 | |
| SCHEMBL15568711 | 0.84 | ALOX5 (0.42) | KDM4EALOX5STAT3NFE2L2PTGS1 | |
| SCHEMBL15567583 | 0.84 | ALOX5 (0.55) | KDM4EALOX5PTGS1ALDH1A1FDPS | |
| SCHEMBL564282 | 0.80 | ALOX5 (0.66) | ALOX5STAT3NFE2L2PTGS1PTGES | |
| SCHEMBL1443525 | 0.79 | FDPS (0.54) | KDM4EALDH1A1FDPSHPGDTDP1 | |
| SCHEMBL20529187 | 0.79 | FDPS (0.54) | KDM4EALDH1A1FDPSTRIM24HPGD | |
| SCHEMBL1515878 | 0.78 | XDH (0.55) | KDM4EALDH1A1HPGDALDH5A1ABAT | |
| SCHEMBL9097669 | 0.78 | FDPS (0.47) | KDM4EALDH1A1FDPSHPGDTDP1 | |
| SCHEMBL13916239 | 0.76 | FDPS (0.41) | KDM4EALDH1A1FDPSSTK17BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537742-B1 | Styrene derivatives | MITSUBISHI CHEM CORP (JP) | 1996-08-21 | — | — | EP | disclosed |