Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28306847 | 0.87 | ADRA2C (0.49) | ADRA2CHPGDMAPTTDP1ALDH1A1 | |
| SCHEMBL17685267 | 0.87 | ADRA2C (0.48) | ADRA2CHPGDMAPTTDP1ALDH1A1 | |
| SCHEMBL28257704 | 0.86 | ADRA2C (0.47) | ADRA2CHPGDMAPTALDH1A1KIF11 | |
| SCHEMBL9065743 | 0.85 | ADRA2C (0.58) | ADRA2CMAPTTDP1KIF11L3MBTL1 | |
| SCHEMBL28270584 | 0.84 | ADRA2C (0.46) | ADRA2CHPGDMAPTTDP1ALDH1A1 | |
| SCHEMBL14327337 | 0.83 | ADRA2C (0.56) | ADRA2CHPGDMAPTTDP1ALDH1A1 | |
| SCHEMBL9775729 | 0.82 | PHLPP2 (0.42) | ADRA2CHPGDMAPTTDP1ALDH1A1 | |
| SCHEMBL1246672 | 0.81 | HDAC3 (0.45) | ADRA2CHPGDMAPTTDP1ALDH1A1 | |
| SCHEMBL28959040 | 0.80 | ROCK1 (0.46) | CYP3A4CES1KMT2ACES2HDAC1 | |
| SCHEMBL1003843 | 0.80 | ADRA2C (0.53) | ADRA2CHPGDALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998055489-A1 | MULTI-CONSTITUENT SYSTEM FOR MODIFYING, DEGRADING OR BLEACHING LIGNIN, MATERIALS CONTAINING LIGNIN OR SIMILAR SUBSTANCES, AND METHOD FOR USING THE SAME | Consortium für elektrochemische Industrie GmbH (DE) | 1998-12-10 | — | — | WO | claimed |
| EP-2394676-B1 | COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITIATOR-CONTAINING SCAFFOLDS | COLOPLAST AS (DK) | 2018-03-28 | — | — | EP | disclosed |
| CN-102516115-B | As the antagonist of Opioid Receptors or the new compound of inverse agonist | SMITHKLINE BEECHAN CORP. (US) | 2016-05-11 | — | — | CN | disclosed |
| CN-103468108-B | Coating composition | COLOPLAST A/S (DK) | 2016-03-02 | — | — | CN | disclosed |
| EP-2459242-B1 | A MEDICAL DEVICE OF POLYOLEFIN | COLOPLAST AS (DK) | 2015-10-21 | — | — | EP | disclosed |
| EP-2104523-B1 | COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS | COLOPLAST AS (DK) | 2015-08-26 | — | — | EP | disclosed |
| US-8932662-B2 | Coatings prepared from poly(ethylene oxide) and photo-initator-containing scaffolds | COLOPLAST A/S (DK) | 2015-01-13 | — | — | US | disclosed |
| CN-103980151-A | Novel compounds as antagonists or inverse agonists at opioid receptors | SMITHKLINE BEECHAM CORP | 2014-08-13 | — | — | CN | disclosed |
| CN-101522614-B | Compounds as antagonists or inverse agonists of opioid receptors | SMITHKLINE BEECHAM CORP | 2014-06-25 | — | — | CN | disclosed |
| US-8568967-B2 | Method for diagnosis of severity and prediction of recurrence in eosinophilic inflammatory disease | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-29 | — | — | US | disclosed |
| US-20100138937-A1 | Method for diagnosis of severity and prediction of recurrence in eosinophilic inflammatory disease | AROS ELECTRONICS AB (SE) | 2010-06-03 | — | — | US | disclosed |
| US-20100049146-A1 | COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS | COLOPLAST A/S (DK) | 2010-02-25 | — | — | US | disclosed |
| EP-2104523-A1 | COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS | Coloplast A/S (DK) | 2009-09-30 | — | — | EP | disclosed |
| CN-101522614-A | Novel compounds as antagonists or inverse agonists of opioid receptors | SMITHKLINE BEECHAM CORP (US) | 2009-09-02 | — | — | CN | disclosed |
| WO-2008071796-A1 | COATINGS PREPARED FROM POLY(ETHYLENE OXIDE) AND PHOTO-INITATOR-CONTAINING SCAFFOLDS | COLOPLAST A/S (DK) | 2008-06-19 | — | — | WO | disclosed |
| EP-1882937-A1 | METHOD FOR DIAGNOSIS OF SEVERITY AND PREDICTION OF RECURRENCE IN EOSINOPHILIC INFLAMMATORY DISEASE | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-30 | — | — | EP | disclosed |
| EP-1685183-A2 | METHOD FOR PRODUCING CARBONYL REST-CONTAINING ORGANOSILICON COMPOUNDS | Wacker Chemie AG (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049697-A2 | METHOD FOR PRODUCING CARBONYL REST-CONTAINING ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2005-06-02 | — | — | WO | disclosed |
| WO-1998055489-A1 | MULTI-CONSTITUENT SYSTEM FOR MODIFYING, DEGRADING OR BLEACHING LIGNIN, MATERIALS CONTAINING LIGNIN OR SIMILAR SUBSTANCES, AND METHOD FOR USING THE SAME | Consortium für elektrochemische Industrie GmbH (DE) | 1998-12-10 | — | — | WO | disclosed |
| EP-0162663-B1 | PROCESS FOR PRODUCING HEAT-RESISTANT MOLDINGS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |