Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15070377 | 0.95 | GABRA1 (0.41) | GABRA1GABRG2GABRB3GABRA3MEN1 | |
| SCHEMBL15070204 | 0.86 | PDE10A (0.39) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL9065796 | 0.83 | MEN1 (0.50) | GABRA1GABRG2GABRB3GABRA3MEN1 | |
| SCHEMBL15070199 | 0.78 | MEN1 (0.46) | GABRA1GABRG2GABRB3GABRA3MEN1 | |
| SCHEMBL15074528 | 0.76 | MAPK1 (0.51) | GABRA1GABRG2GABRB3GABRA3MEN1 | |
| SCHEMBL15070203 | 0.72 | GABRA1 (0.47) | GABRA1GABRG2GABRB3GABRA3MEN1 | |
| SCHEMBL10462205 | 0.70 | GABRA1 (0.53) | GABRA1GABRG2GABRB3GABRA3MEN1 | |
| SCHEMBL10460993 | 0.69 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA3MEN1 | |
| SCHEMBL3519072 | 0.69 | GABRA1 (0.54) | GABRA1GABRG2GABRB3GABRA3MEN1 | |
| SCHEMBL16065450 | 0.68 | ROCK2 (0.46) | ALDH1A1GAACYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165483-A1 | HETEROARYLS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-06-27 | — | — | US | disclosed |
| US-5583148-A | FUNGICIDE, BACTERICIDE AND ANTICARCINOGENIC AGENT | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165483-A1 | HETEROARYLS AND USES THEREOF | PIK3R5, PIK3R4, PIK3C2B | GABRA1 2837/4885GABRG2 2206/4885GABRB3 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.