Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730344 | 0.88 | ALDH1A1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL646412 | 0.80 | THRB (0.38) | — | |
| SCHEMBL704023 | 0.80 | THRB (0.38) | — | |
| SCHEMBL478006 | 0.78 | THRB (0.36) | — | |
| SCHEMBL3104636 | 0.78 | THRB (0.36) | — | |
| SCHEMBL6007776 | 0.78 | THRB (0.36) | — | |
| SCHEMBL28007711 | 0.78 | CYP1A2 (0.35) | TSHRALDH1A1 | |
| SCHEMBL27491447 | 0.76 | THRB (0.35) | — | |
| SCHEMBL554261 | 0.75 | CYP2C19 (0.33) | TSHRALDH1A1 | |
| SCHEMBL331066 | 0.75 | THRB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708143-A1 | Polyvinyl chloride based resin composition and products derived therefrom | SEKISUI AMERICA CORPORATION (US) | 1996-04-24 | — | — | EP | disclosed |