Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | PAM | P19021 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065489 | 0.79 | MGAM (0.37) | MGAMGAASIMGAM2 | |
| SCHEMBL11703203 | 0.78 | EPHX1 (0.38) | FAAHFDPSEPHX1NAAADGKA | |
| SCHEMBL28727569 | 0.78 | CA1 (0.39) | FDPSEPHX1CA1CA2MGAM | |
| SCHEMBL28026913 | 0.72 | GPR84 (0.42) | PAMALDH1A1MEN1KMT2A | |
| SCHEMBL2957094 | 0.71 | MGAM (0.37) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL9065496 | 0.71 | LDHA (0.31) | — | |
| SCHEMBL11703210 | 0.70 | AKR1B1 (0.38) | PAMALDH1A1MEN1KMT2A | |
| SCHEMBL27813236 | 0.70 | FDPS (0.37) | FDPSEPHX1CA1CA2ALDH1A1 | |
| SCHEMBL28691157 | 0.69 | AKR1B1 (0.34) | FDPSPAMALDH1A1MEN1KMT2A | |
| SCHEMBL12776906 | 0.69 | ALDH1A1 (0.41) | FAAHFDPSEPHX1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5569780-A | Dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1996-10-29 | — | — | US | disclosed |
| US-5463111-A | Process for preparing dialkyl 2-haloethyl malonates | HULS AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |