Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066286 | 0.84 | ESR2 (0.41) | ESR1ESR2GABRA1GABRB2SOAT1 | |
| SCHEMBL9073788 | 0.75 | SOAT1 (0.33) | ESR1ESR2GABRA1GABRB2SOAT1 | |
| SCHEMBL9065904 | 0.74 | ESR2 (0.39) | ESR1ESR2HPGDMAPT | |
| SCHEMBL9066250 | 0.73 | ESR2 (0.42) | ESR1ESR2GRIN2BMAPT | |
| SCHEMBL16581372 | 0.72 | ESR2 (0.41) | ESR1ESR2CYP3A4GRIN2BMAPT | |
| SCHEMBL27259988 | 0.69 | ADRA2A (0.47) | GABRA1GABRB2FAAHCA1CA2 | |
| SCHEMBL9437447 | 0.68 | ESR2 (0.56) | ESR1ESR2CA1CA2LMNA | |
| SCHEMBL9073371 | 0.67 | ESR1 (0.51) | ESR1ESR2GABRA1GABRB2LMNA | |
| SCHEMBL9075536 | 0.66 | ACHE (0.45) | ESR1ESR2GABRA1GABRB2FAAH | |
| SCHEMBL19523190 | 0.66 | ADRA2A (0.42) | GABRA1GABRB2FAAHCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469403-B1 | High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-B1 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-A2 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |