SCHEMBL9066286

SCHEMBL9066286

CC(C)c1ccccc1C1CCCC(c2ccc(O)cc2)(c2ccc(O)cc2)C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 5/20 0.41
ESR1 P03372 3/20 0.41
TRPA1 O75762 1/20 0.34
ALDH1A1 P00352 1/20 0.33
PLA2G1B P04054 1/20 0.33
ATG4B Q9Y4P1 1/20 0.33
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
SOAT1 P35610 1/20 0.32
OPRM1 P35372 1/20 0.31
OPRK1 P41145 1/20 0.31
FAAH O00519 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
GABRB1 P18505 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065901 0.84 ESR1 (0.37) ESR2ESR1ALDH1A1PLA2G1BATG4B
SCHEMBL2043249 0.76 TRPA1 (0.54) ESR2ESR1TRPA1CYP3A4
SCHEMBL16581407 0.75 TRPA1 (0.49) ESR2ESR1TRPA1CYP3A4
SCHEMBL16581404 0.74 ESR2 (0.55) ESR2ESR1TRPA1CYP3A4
SCHEMBL9073788 0.73 SOAT1 (0.33) ESR2ESR1ALDH1A1PLA2G1BATG4B
SCHEMBL19523190 0.72 ADRA2A (0.42) ALDH1A1PLA2G1BATG4BGABRA1GABRB2
SCHEMBL9074035 0.72 ESR2 (0.52) ESR2ESR1ALDH1A1OPRM1OPRK1
Hydrogen Peroxide SCHEMBL11527811 0.71 PTGDR2 (0.44) ALDH1A1PLA2G1BATG4BGABRA1GABRB2
SCHEMBL22811872 0.71 ESR1 (0.50) ESR2ESR1ALDH1A1
SCHEMBL5600840 0.70 PTGS2 (0.41) ALDH1A1PLA2G1BATG4BGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0469403-B1 High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-B1 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1996-02-28 EP disclosed
EP-0469404-A2 Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof BAYER AG (DE) 1992-02-05 EP disclosed