Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075536 | 0.87 | ACHE (0.45) | ESR1ESR2GABRA1GABRB2KMT2A | |
| SCHEMBL9066299 | 0.79 | ESR2 (0.59) | ESR1ESR2TAS1R3TAS1R1KMT2A | |
| SCHEMBL4816643 | 0.76 | ESR2 (0.63) | ESR1ESR2KMT2AMAPTMEN1 | |
| SCHEMBL4065863 | 0.76 | ESR1 (0.63) | ESR1ESR2KMT2AMAPTMEN1 | |
| SCHEMBL5386114 | 0.75 | ESR1 (0.71) | ESR1ESR2KMT2AMAPTMEN1 | |
| SCHEMBL30165897 | 0.73 | ESR1 (0.69) | ESR1ESR2KMT2AMAPTMEN1 | |
| SCHEMBL29393324 | 0.73 | ESR1 (0.69) | ESR1ESR2KMT2AMAPTMEN1 | |
| SCHEMBL4200651 | 0.73 | ESR1 (0.69) | ESR1ESR2KMT2AMAPTMEN1 | |
| SCHEMBL30375487 | 0.73 | ESR2 (0.59) | ESR1ESR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3807813 | 0.73 | ESR2 (0.59) | ESR1ESR2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469403-B1 | High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-A2 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |