Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HBB | P68871 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Famciclovir SCHEMBL4166714 | 0.88 | HSD17B10 (0.66) | HSD17B10ALDH1A1KDM4EHPGDADRA1A | |
| Famciclovir SCHEMBL20570567 | 0.84 | MEN1 (0.59) | HSD17B10ALDH1A1KDM4EHPGDADRA1A | |
| Famciclovir SCHEMBL18526964 | 0.83 | MEN1 (0.58) | HSD17B10ALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL7496272 | 0.81 | MEN1 (0.68) | HSD17B10ALDH1A1MEN1KMT2AHBB | |
| Hydrochloric Acid SCHEMBL4908550 | 0.80 | HBB (0.69) | HSD17B10ALDH1A1MEN1KMT2AHBB | |
| Hydrochloric Acid SCHEMBL9414134 | 0.80 | HBB (0.68) | HSD17B10ALDH1A1MEN1KMT2AHBB | |
| Hydrochloric Acid SCHEMBL9275315 | 0.80 | HBB (0.68) | HSD17B10ALDH1A1MEN1KMT2AHBB | |
| Famciclovir SCHEMBL384993 | 0.77 | ALDH1A1 (0.69) | HSD17B10ALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL5930085 | 0.77 | TK1 (0.56) | HSD17B10ALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL5930196 | 0.76 | ALDH1A1 (0.59) | HSD17B10ALDH1A1KDM4EHPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022098-A1 | USE OF ACYCLIC PURINE DERIVATIVES FOR TREATING RESTENOSIS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-07-25 | — | — | WO | claimed |