SCHEMBL7790474

SCHEMBL7790474

Nc1ccc2cc(S(=O)(=O)O)c(N)c(O)c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.57
CASP6 P55212 4/20 0.45
NSD2 O96028 2/20 0.45
DUSP3 P51452 1/20 0.45
PTPN5 P54829 1/20 0.45
PTPN11 Q06124 1/20 0.45
ENPP2 Q13822 1/20 0.42
RAPGEF4 Q8WZA2 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
ALDH1A1 P00352 8/20 0.40
HSD17B10 Q99714 5/20 0.40
TDP1 Q9NUW8 4/20 0.40
CASP1 P29466 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
CASP7 P55210 1/20 0.40
RECQL P46063 4/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
POLB P06746 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10014029 0.88 CASP6 (0.55) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL9066446 0.84 NT5E (0.58) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL6017882 0.84 NT5E (0.41) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL16454269 0.83 ALDH1A1 (0.42) NT5ECASP6ALDH1A1HSD17B10TDP1
SCHEMBL5694580 0.81 CTRB1 (0.48) CASP6ALDH1A1TDP1RECQLMAPT
SCHEMBL14339180 0.81 ALDH1A1 (0.38) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL4649791 0.80 NT5E (0.50) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL5857990 0.79 NT5E (0.49) NT5ECASP6NSD2DUSP3PTPN5
SCHEMBL10634937 0.77 ENPP2 (0.58) NT5EENPP2CYP2C9CYP1A2
SCHEMBL27559667 0.77 MEN1 (0.41) NT5ECASP6NSD2ENPP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3578162-B1 HAIR TREATMENT METHOD KAO CORP (JP) 2024-06-26 EP disclosed
EP-3626224-B1 MULTIAGENT-TYPE HAIR TREATMENT AGENT KAO CORP (JP) 2023-12-13 EP disclosed
WO-2023181691-A1 HAIR WASHING COMPOSITION 花王株式会社 2023-09-28 WO disclosed
US-11523977-B2 Multi-agent type hair treatment agent KAO CORPORATION (JP) 2022-12-13 US disclosed
CN-110198702-B Hair treatment method 花王株式会社 2022-11-29 CN disclosed
US-20220226216-A1 HAIR TREATMENT METHOD KAO CORPORATION (JP) 2022-07-21 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
CN-114080217-A Hair cosmetic 花王株式会社 2022-02-22 CN disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
CN-108366943-B Hair treatment method 花王株式会社 2022-01-25 CN disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11523977-B2 Multi-agent type hair treatment agent POLR1C, SHH, PIK3C3 NT5E 3747/4885CASP6 1926/4885NSD2 495/4885
US-20220226216-A1 HAIR TREATMENT METHOD POLR1C, ALDH7A1, CA7 NT5E 3725/4885CASP6 1124/4885NSD2 3082/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 NT5E 4267/4885CASP6 3673/4885NSD2 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.