SCHEMBL9067264

SCHEMBL9067264

NN1CCc2ccccc2O1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.38
MAOB P27338 3/20 0.38
DRD2 P14416 2/20 0.38
DRD1 P21728 1/20 0.38
DRD4 P21917 1/20 0.38
DRD5 P21918 1/20 0.38
DRD3 P35462 1/20 0.38
ALDH1A1 P00352 2/20 0.35
ALOX15 P16050 2/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
CDK4 P11802 1/20 0.35
CCND1 P24385 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR1A P08908 2/20 0.35
ADRA2A P08913 2/20 0.35
TMPRSS2 O15393 1/20 0.35
CYP2D6 P10635 1/20 0.35
SLC6A2 P23975 1/20 0.35
SIGMAR1 Q99720 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6645559 0.78 MAOA (0.39) MAOAMAOBALDH1A1MEN1KMT2A
SCHEMBL14908518 0.77 DRD2 (0.48) MAOAMAOBDRD2DRD1DRD4
SCHEMBL28284813 0.75 SIGMAR1 (0.38) MAOAMAOBDRD2DRD1DRD4
SCHEMBL27888669 0.71 KMT2A (0.35) MAOAMAOBDRD2DRD1DRD4
SCHEMBL13966505 0.71 DRD1 (0.38) MAOAMAOBDRD2DRD1DRD4
SCHEMBL13976100 0.71 DRD2 (0.40) MAOAMAOBDRD2DRD1DRD4
SCHEMBL9615962 0.68 SETD7 (0.59) MAOAMAOBDRD2DRD1DRD4
SCHEMBL4794961 0.67 MAOA (0.52) MAOAMAOBDRD2DRD1DRD4
SCHEMBL1774397 0.67 PRCP (0.46) DRD1DRD5HTR1AADRA2ACYP2D6
SCHEMBL56392 0.66 ABCG2 (0.36) MAOAMAOBALOX15LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543086-A ABSORBER USED IN TRANSPARENT PLASTICS GENTEX CORPORATION (US) 1996-08-06 US disclosed