Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067915 | 0.86 | LMNA (0.39) | F2CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL9067048 | 0.83 | F2 (0.45) | F2CYP3A4CYP2D6CYP2C19PTPN1 | |
| SCHEMBL9068100 | 0.76 | CYP3A4 (0.46) | F2CYP3A4CYP2D6CYP2C19PTPN1 | |
| SCHEMBL28008650 | 0.76 | F2 (0.48) | F2CYP3A4CYP2D6CYP2C19PTPN1 | |
| SCHEMBL9067420 | 0.74 | SMN1; SMN2 (0.42) | F2SMN1; SMN2F10MMP8ALDH1A1 | |
| SCHEMBL7017101 | 0.73 | F2 (0.46) | F2CYP3A4CYP2D6CYP2C19PTPN1 | |
| SCHEMBL9067050 | 0.72 | CYP3A4 (0.42) | F2CYP3A4CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL8532811 | 0.72 | L3MBTL1 (0.35) | GAA | |
| SCHEMBL28633131 | 0.71 | SMN1; SMN2 (0.51) | CYP3A4CYP2D6CYP2C19PTPN1SMN1; SMN2 | |
| SCHEMBL29756122 | 0.70 | CYP3A4 (0.48) | F2CYP3A4CYP2D6CYP2C19PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |