Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8530708 | 0.81 | ALDH1A1 (0.37) | KMT2APOLBGAA | |
| SCHEMBL8528852 | 0.80 | L3MBTL1 (0.44) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL9067415 | 0.72 | F2 (0.40) | GAA | |
| SCHEMBL4036129 | 0.70 | L3MBTL1 (0.49) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL8797962 | 0.70 | L3MBTL1 (0.35) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL9067638 | 0.69 | L3MBTL1 (0.35) | L3MBTL1KMT2APOLBCYP1A2 | |
| SCHEMBL11652884 | 0.69 | GABRP (0.48) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL18561876 | 0.69 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL8410329 | 0.69 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2MGAM | |
| SCHEMBL8410331 | 0.69 | L3MBTL1 (0.50) | L3MBTL1KMT2APOLBCYP1A2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773428-A | BONE DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1996023791-A1 | BRIDGED INDOLES AS MATRIX METALLOPROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1996-08-08 | — | — | WO | disclosed |