Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | MMP16 | P51512 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422355 | 0.91 | HTR6 (0.47) | HTR6NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL9874252 | 0.90 | MAOA (0.46) | HTR6NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL10936886 | 0.88 | ESR1 (0.44) | HTR6ALDH1A1HPGDHTTSMN1; SMN2 | |
| SCHEMBL9234281 | 0.82 | HTR6 (0.45) | HTR6ALDH1A1HPGDMMP2MMP9 | |
| SCHEMBL10709549 | 0.82 | HTR6 (0.50) | HTR6MAPTHTTSMN1; SMN2MMP2 | |
| SCHEMBL9494015 | 0.82 | HTR6 (0.53) | HTR6MAPTHTTSMN1; SMN2MMP2 | |
| SCHEMBL30016251 | 0.82 | NCOA1 (0.44) | HTR6NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL28394438 | 0.82 | NCOA1 (0.44) | HTR6NPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL14062243 | 0.81 | HTR6 (0.58) | HTR6MAPTALDH1A1HTTMMP2 | |
| SCHEMBL5831246 | 0.80 | HTR6 (0.56) | HTR6NPC1RAB9AALDH1A1NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6322128-A | — | — | None | — | — | JP | disclosed |
| US-5506311-A | HEAT RESISTANCE, MELT PROCESSIBILITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-04-09 | — | — | US | disclosed |
| US-5380805-A | Polyamideimide copolymers for heat resistance and high temperature engineering polymers | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5380820-A | Heat resistance | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-01-10 | — | — | US | disclosed |
| JP-H06322128-A | AROMATIC POLYAMIDEIMIDE RESIN AND RESIN COMPOSITION | MITSUI TOATSU CHEM INC | 1994-11-22 | — | — | JP | disclosed |
| US-5288843-A | Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-02-22 | — | — | US | disclosed |