Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP14 | P50281 | 2/20 | 0.40 |
| ▸ | MMP16 | P51512 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874252 | 0.99 | MAOA (0.46) | HTR6NCOA1NCOA3MAOAKDM1A | |
| SCHEMBL9067458 | 0.91 | HTR6 (0.43) | HTR6NCOA1NCOA3MAOAKDM1A | |
| SCHEMBL10709549 | 0.90 | HTR6 (0.50) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL30016251 | 0.90 | NCOA1 (0.44) | HTR6NCOA1NCOA3MAOAKDM1A | |
| SCHEMBL28394438 | 0.90 | NCOA1 (0.44) | HTR6NCOA1NCOA3MAOAKDM1A | |
| SCHEMBL9494015 | 0.90 | HTR6 (0.53) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL5831246 | 0.88 | HTR6 (0.56) | HTR6NCOA1NCOA3MAOAMMP2 | |
| SCHEMBL2159027 | 0.86 | MAOB (0.49) | HTR6HTTTSHRLMNAALDH1A1 | |
| SCHEMBL14062243 | 0.86 | HTR6 (0.58) | HTR6MMP2MMP9MMP8MMP12 | |
| SCHEMBL14060647 | 0.86 | HTR6 (0.46) | HTR6MMP2MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118848-A | Converting 4-aminophenol to alkali metal phenolate, reacting with 4,4'-dihalophenyl sulfone, precipitation, separation-using dialkylamide or N-alkyl lactam solvent | HUELS AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | claimed |
| US-4636535-A | NONSILICEOUS, REINFORCEMENT, FILAMENTS, POLYEPOXY MONOMER, DIAMINODIPHENYL DIESTER CURING AGENT | AMERICAN CYANAMID COMPANY (US) | 1987-01-13 | — | — | US | claimed |
| EP-0189048-A2 | Curable epoxy resin compositions | AMERICAN CYANAMID COMPANY (US) | 1986-07-30 | — | — | EP | claimed |
| WO-1994016017-A1 | POLYMER COMPOSITION | DSM N.V. (NL) | 1994-07-21 | — | — | WO | disclosed |
| US-4864009-A | Molding composition consisting of aliphatic/aromatic copolyamide | HUELS AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0312771-A1 | Thermosetting resin systems containing secondary amine-terminated siloxane modifiers | BASF Aktiengesellschaft (DE) | 1989-04-26 | — | — | EP | disclosed |
| EP-0194865-A2 | Soluble polyimide-siloxane precursor, process for producing same and cross-linked polyimide-siloxane | Chisso Corporation (JP) | 1986-09-17 | — | — | EP | disclosed |
| EP-0127198-A1 | Preimpregnated reinforcements and high strength composites therefrom | AMOCO CORPORATION (US) | 1984-12-05 | — | — | EP | disclosed |