SCHEMBL906750

SCHEMBL906750

Cc1cc2ccccc2nc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
KDM4E B2RXH2 4/20 0.59
HPGD P15428 3/20 0.59
GAA P10253 2/20 0.59
TDP1 Q9NUW8 1/20 0.59
STAT3 P40763 1/20 0.59
PDE10A Q9Y233 1/20 0.55
GLA P06280 2/20 0.52
MAPT P10636 2/20 0.52
ACHE P22303 1/20 0.52
MBNL1 Q9NR56 1/20 0.49
NQO2 P16083 1/20 0.46
CYP1A2 P05177 3/20 0.45
TTR P02766 1/20 0.44
MIF P14174 1/20 0.43
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
TLR8 Q9NR97 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31122649 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDGAATDP1
SCHEMBL7184557 0.98 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDGAATDP1
SCHEMBL30486684 0.77 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDGAATDP1
SCHEMBL7159163 0.77 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDGAATDP1
SCHEMBL22326435 0.77 PDE10A (0.77) ALDH1A1KDM4EHPGDGAATDP1
SCHEMBL38652592 0.77 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDGAATDP1
SCHEMBL422035 0.77 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDGAATDP1
SCHEMBL209889 0.77 ALDH1A1 (0.63) ALDH1A1KDM4EHPGDGAATDP1
SCHEMBL8340066 0.77 CYP1A2 (0.50) ALDH1A1KDM4EHPGDGAATDP1
Hydrochloric Acid SCHEMBL7361242 0.76 ALDH1A1 (0.61) ALDH1A1KDM4EHPGDGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111704633-A Mo catalyst and application thereof in preparation of 9, 10-epoxy-1, 5-cyclododecadiene 万华化学集团股份有限公司 2020-09-25 CN claimed
US-8623519-B2 Red phosphorescent compound and organic electroluminescent device using the same LG DISPLAY CO., LTD. (KR) 2014-01-07 US claimed
EP-0140347-A2 Fluorescent corrosive fluoride solution UNION CARBIDE CORPORATION (US) 1985-05-08 EP claimed
CN-117986220-A Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2024-05-07 CN disclosed
CN-114222734-B Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2023-12-08 CN disclosed
EP-4227304-A2 THIADIAZOLE ANALOGS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH A DEFICIENCY OF SMN MOTOR NEURONS Novartis AG (CH) 2023-08-16 EP disclosed
US-20230027684-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. 2023-01-26 US disclosed
CN-114222734-A Method for preparing substituted chromanone derivative 杭州杜易科技有限公司 2022-03-22 CN disclosed
CN-113613732-A Liquid hair dye composition 花王株式会社 2021-11-05 CN disclosed
EP-3736271-A1 THIADIAZOLE ANALOGS AND THEIR USE FOR TREATING DISEASES ASSOCIATED WITH A DEFICIENCY OF SMN MOTOR NEURONS Novartis AG (CH) 2020-11-11 EP disclosed
CN-111704633-A Mo catalyst and application thereof in preparation of 9, 10-epoxy-1, 5-cyclododecadiene 万华化学集团股份有限公司 2020-09-25 CN disclosed
US-20040247937-A1 Organic electroluminescent devices with a doped co-host emitter E-RAY OPTELECTRONICS TECHNOLOGY CO., LTD. (TW) 2004-12-09 US disclosed
US-20040126439-A1 Composition useful as hepatoprotectants comprising extract of plant cryptolepis buchanani and a method thereof OAZI GHULAM NABI 2004-07-01 US disclosed
US-6686375-B2 Composition useful as hepatoprotectants comprising extract of plant Cryptolepis buchanani and a method thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-02-03 US disclosed
US-20030185906-A1 Composition useful as hepatoprotectants comprising extract of plant Cryptolepis Buchanani and a method thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-02 US disclosed
US-6548086-B1 Controlling immunology response; administering plant extract;side effect reduction COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-04-15 US disclosed
EP-1121385-A1 ELASTOMERIC POLYMER VEHICLE PARTS HAVING IMPROVED LOW-TEMPERATURE COMPRESSION SET ExxonMobil Chemical Patents Inc. (US) 2001-08-08 EP disclosed
WO-2000022015-A9 ELASTOMERIC POLYMER VEHICLE PARTS HAVING IMPROVED LOW-TEMPERATURE COMPRESSION SET EXXON CHEMICAL PATENTS INC (US) 2000-10-12 WO disclosed
WO-2000022014-A1 ELASTOMERIC POLYMER VEHICLE PARTS HAVING IMPROVED LOW TEMPERATURE COMPRESSION SET EXXON CHEMICAL PATENTS INC. (US) 2000-04-20 WO disclosed
WO-2000022015-A1 ELASTOMERIC POLYMER VEHICLE PARTS HAVING IMPROVED LOW-TEMPERATURE COMPRESSION SET EXXON CHEMICAL PATENTS INC. (US) 2000-04-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027684-A1 METHODS AND COMPOSITIONS FOR MODULATING SPLICING RBM17, SF3B1, SF3B5 ALDH1A1 3964/4885KDM4E 2544/4885HPGD 3316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.