Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1955171 | 0.84 | TSHR (0.47) | TSHRACHEALDH1A1TDP1ESR1 | |
| Acetic Acid SCHEMBL9068177 | 0.81 | ALDH1A1 (0.39) | TSHRACHEHPGDHSD17B10ALDH1A1 | |
| Phosphoric Acid SCHEMBL7200448 | 0.78 | ACP3 (0.36) | TSHRACHEHPGDACP3HSD17B10 | |
| O-Xylene SCHEMBL38665313 | 0.76 | TSHR (0.59) | TSHRACHEHPGDACP3HSD17B10 | |
| O-Xylene SCHEMBL10690565 | 0.76 | TSHR (0.59) | TSHRACHEHPGDACP3HSD17B10 | |
| SCHEMBL8376844 | 0.75 | PGR (0.33) | TSHRACHEHPGDALDH1A1TDP1 | |
| Phosphoric Acid SCHEMBL9067731 | 0.75 | ACP3 (0.34) | HPGDACP3ALDH1A1TDP1 | |
| Phosphoric Acid SCHEMBL7195799 | 0.74 | LAP3 (0.40) | TSHRHPGDACP3ALDH1A1L3MBTL1 | |
| SCHEMBL9777686 | 0.74 | GAA (0.41) | ALDH1A1TDP1CA1CA2CA7 | |
| Phosphoric Acid SCHEMBL7195775 | 0.72 | ACP3 (0.36) | HPGDACP3ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534565-A | DICYANDIAMIDE DERIVATIVES FOR LAMINATES | ALLIEDSIGNAL INC. (US) | 1996-07-09 | — | — | US | disclosed |
| WO-1994014866-A1 | SOLVENT FREE EPOXY RESIN COMPOSITIONS | ALLIEDSIGNAL, INC. (US) | 1994-07-07 | — | — | WO | disclosed |