SCHEMBL9067964

SCHEMBL9067964

C#CCc1ccc(C=C)cc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.34
HDAC8 Q9BY41 1/20 0.33
PIK3CG P48736 1/20 0.33
POLB P06746 1/20 0.31
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28781884 0.79 ALDH1A1 (0.52) ALDH1A1TSHRTDP1HDAC8PIK3CG
SCHEMBL4137976 0.77 CYP2A6 (0.41) ALDH1A1
SCHEMBL350919 0.77 ALDH1A1 (0.50) ALDH1A1TSHRTDP1HDAC8PIK3CG
SCHEMBL10339591 0.74 ALDH1A1 (0.41) ALDH1A1TSHRCHRNB2CHRNB4CHRNA3
SCHEMBL11193453 0.73 PYCR1 (0.30)
SCHEMBL50012 0.72 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL50300 0.72 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL1647493 0.72 ALDH1A1 (0.65) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL473081 0.71 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8CHRNB2
SCHEMBL7639 0.71 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0537972-B1 Treating solution for contact lenses NOF CORP (JP) 1996-07-10 EP claimed