Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734436 | 0.90 | SMN1; SMN2 (0.35) | L3MBTL1TSHRAGTR1LMNACYP1A2 | |
| SCHEMBL9261650 | 0.89 | TAS1R3 (0.36) | TSHRNFE2L2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9068000 | 0.87 | AGTR1 (0.39) | L3MBTL1TSHRAGTR1LMNACYP1A2 | |
| SCHEMBL5023010 | 0.84 | CHRM2 (0.36) | NFE2L2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3238217 | 0.83 | ALDH1A1 (0.43) | L3MBTL1TSHRAGTR1LMNACYP1A2 | |
| SCHEMBL8729134 | 0.83 | NFE2L2 (0.41) | TSHRNFE2L2SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL6854669 | 0.82 | AGTR1 (0.38) | L3MBTL1TSHRAGTR1LMNACYP1A2 | |
| SCHEMBL9559238 | 0.82 | NFE2L2 (0.34) | NFE2L2SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL9453918 | 0.81 | AGTR1 (0.39) | L3MBTL1TSHRAGTR1LMNACYP1A2 | |
| SCHEMBL6464526 | 0.79 | HPGD (0.39) | KDM4ESMN1; SMN2KMT2AATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427458-A | Transglutaminase mediated conjugation | 塔拉克治疗公司 | 2022-12-02 | — | — | CN | disclosed |
| WO-1996034008-A1 | NOVEL ANTISENSE NUCLEIC ACIDS DIRECTED AGAINST RAS ONCOGENES, THEIR PREPARATION AND USE | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1996-10-31 | — | — | WO | disclosed |