Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063512 | 0.86 | KMT2A (0.41) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL2851129 | 0.83 | KMT2A (0.58) | SMN1; SMN2CYP26A1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL3375103 | 0.83 | KMT2A (0.58) | SMN1; SMN2CYP26A1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL640977 | 0.83 | KMT2A (0.58) | SMN1; SMN2CYP26A1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL28201839 | 0.83 | ALDH1A1 (0.59) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8577983 | 0.80 | TGFBR1 (0.41) | ALDH1A1ATML3MBTL1KDM4E | |
| SCHEMBL14278805 | 0.79 | ITGB3 (0.47) | SMN1; SMN2CYP26A1ALDH1A1ATML3MBTL1 | |
| SCHEMBL6857593 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2CYP26A1ALDH1A1ATML3MBTL1 | |
| SCHEMBL472254 | 0.78 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11508098 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5549807-A | Thermoplastic composites formed by electropolymerization of N-substituted methacrylamide monomers | THE UNIVERSITY OF CONNECTICUT (US) | 1996-08-27 | — | — | US | claimed |
| US-5238542-A | Onto electrically conductive filler | THE UNIVERSITY OF CONNECTICUT (US) | 1993-08-24 | — | — | US | claimed |