Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30692863 | 0.90 | POLB (0.36) | GABRA1GABRB2POLB | |
| SCHEMBL9237411 | 0.90 | POLB (0.36) | GABRA1GABRB2POLB | |
| SCHEMBL8903316 | 0.88 | GABRA1 (0.38) | GABRA1GABRB2RXRAPPARGRARG | |
| SCHEMBL9068739 | 0.87 | APEX1 (0.36) | RXRAPPARGRARGALDH1A1TDP1 | |
| SCHEMBL9238574 | 0.83 | SMN1; SMN2 (0.45) | POLBALDH1A1TSHRTDP1CYP1A2 | |
| SCHEMBL11425104 | 0.83 | ALDH1A1 (0.31) | ALDH1A1TSHRTDP1KDM4ECYP1A2 | |
| SCHEMBL2517646 | 0.83 | GABRA1 (0.36) | GABRA1GABRB2GABBR2GABBR1RXRA | |
| SCHEMBL17150116 | 0.81 | RXRA (0.35) | GABRA1GABRB2RXRAPPARGRARG | |
| SCHEMBL8961411 | 0.80 | GABRA1 (0.31) | GABRA1GABRB2RXRAPPARGRARG | |
| SCHEMBL11421838 | 0.79 | GABRA1 (0.38) | GABRA1GABRB2GABBR2GABBR1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584146-A | Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites | THE B. F. GOODRICH COMPANY (US) | 1986-04-22 | — | — | US | claimed |
| US-5521237-A | HEAT, OXIDATION, AND RADIATION RESISTANT POLYOLEFINS FOR PROTECTIVE COATINGS THAT RESIST DISCOLORATION | CIBA-GEIGY CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| US-4584146-A | Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites | THE B. F. GOODRICH COMPANY (US) | 1986-04-22 | — | — | US | disclosed |
| US-4233208-A | OXIDATION RESISTANCE, RADIATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |