SCHEMBL8961411

SCHEMBL8961411

CC(C)(C)c1cc(C(C)(C)C)c(OP(OCl)OCl)c(C(C)(C)C)c1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
RARG P13631 1/20 0.30
RXRA P19793 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27390838 0.91 POLB (0.34)
SCHEMBL2517646 0.88 GABRA1 (0.36) GABRA1GABRB2RARGRXRAPPARG
SCHEMBL26698102 0.82 RARG (0.33) GABRA1GABRB2RARGRXRAPPARG
SCHEMBL8903316 0.80 GABRA1 (0.38) GABRA1GABRB2RARGRXRAPPARG
SCHEMBL9068331 0.80 GABRA1 (0.33) GABRA1GABRB2RARGRXRAPPARG
SCHEMBL28777872 0.79 CYP2C19 (0.31) GABRA1GABRB2
SCHEMBL10999888 0.78 CA2 (0.40) GABRA1GABRB2
SCHEMBL3362205 0.78 POLB (0.39) GABRA1GABRB2RARGRXRAPPARG
SCHEMBL26698101 0.78 RXRA (0.34) RARGRXRAPPARG
SCHEMBL17150116 0.78 RXRA (0.35) GABRA1GABRB2RARGRXRAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0487036-B1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC (US) 1996-02-07 EP disclosed
US-5326801-A Photoresistance, heat resistance, oxidation resistance HIMONT INCORPORATED (US) 1994-07-05 US disclosed
US-5162548-A ORGANIC PHOSPHITES SUITABLE AS STABILIZERS FOR POLYMERS HIMONT INCORPORATED (US) 1992-11-10 US disclosed
EP-0487036-A1 Organic phosphites suitable as stabilizers and polymer compositions comprising them MONTELL NORTH AMERICA INC. (US) 1992-05-27 EP disclosed