Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684693 | 0.87 | POLB (0.48) | MEN1KMT2ATDP1ALDH1A1POLB | |
| SCHEMBL38656 | 0.86 | ALDH1A1 (0.43) | MEN1KMT2ATDP1KDM4EGAA | |
| SCHEMBL7721046 | 0.84 | ABL1 (0.38) | MEN1KMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL9068184 | 0.82 | MEN1 (0.52) | MEN1KMT2ASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL8436391 | 0.82 | CES1 (0.44) | MEN1KMT2ATDP1KDM4EGAA | |
| SCHEMBL8952018 | 0.79 | MAPT (0.50) | SMN1; SMN2CYP3A4L3MBTL1TDP1KDM4E | |
| SCHEMBL8068727 | 0.78 | MGLL (0.41) | MEN1KMT2ASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL993051 | 0.78 | MCL1 (0.45) | MEN1KMT2ASMN1; SMN2GAANPC1 | |
| SCHEMBL9068188 | 0.77 | ABL1 (0.34) | SMN1; SMN2KDM4EGAALMNA | |
| SCHEMBL1933595 | 0.76 | MCL1 (0.44) | MEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491200-A | FORMING GRAFT OR BLOCK COPOLYMER FROM POLYIMIDE ENDCAPPED WITH ACYL-ACTIVATED CAPROLACTAM RING AND MOLTEN CAPROLACTAM; FIBER BLENDS WITH NYLON-6; HEAT, CHEMICAL RESISTANT | EDISON POLYMER INNOVATION CORPORATION (US) | 1996-02-13 | — | — | US | disclosed |