Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.34 |
| ▸ | PLOD3 | O60568 | 2/20 | 0.34 |
| ▸ | PLOD1 | Q02809 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL158703 | 0.93 | NAPRT (0.50) | NAPRTTSHRTDP1L3MBTL1HRH4 | |
| Trifluoroacetic Acid SCHEMBL9068482 | 0.93 | NAPRT (0.50) | NAPRTTSHRTDP1L3MBTL1HRH4 | |
| Trifluoroacetic Acid SCHEMBL16824180 | 0.93 | NAPRT (0.50) | NAPRTTSHRTDP1L3MBTL1HRH4 | |
| Trifluoroacetic Acid SCHEMBL6076010 | 0.90 | NAPRT (0.47) | NAPRTTSHRTDP1L3MBTL1HRH4 | |
| Trifluoroacetic Acid SCHEMBL27559395 | 0.90 | NAPRT (0.47) | NAPRTTSHRTDP1L3MBTL1HRH4 | |
| Trifluoroacetic Acid SCHEMBL28316548 | 0.88 | TSHR (0.41) | NAPRTTSHRTDP1L3MBTL1HRH4 | |
| Trifluoroacetamide SCHEMBL28778857 | 0.83 | NAPRT (0.45) | NAPRTTSHRTDP1L3MBTL1PLOD2 | |
| Trifluoroacetic Acid SCHEMBL8138931 | 0.82 | PLOD2 (0.40) | NAPRTTSHRTDP1L3MBTL1HRH4 | |
| Trifluoromethanesulfonic Acid SCHEMBL27353707 | 0.80 | L3MBTL1 (0.43) | NAPRTTSHRTDP1L3MBTL1UBE2N | |
| Trifluoroacetic Acid SCHEMBL28325627 | 0.80 | TSHR (0.38) | NAPRTTSHRTDP1L3MBTL1UBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324197-B2 | Transplatinum complexes with N2O2 donor sets as cytotoxic and antitumor agents | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2012-12-04 | — | — | US | disclosed |
| US-20070082882-A1 | Transplatinum complexes with N2O2 donor sets as cytotoxic and antitumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082882-A1 | Transplatinum complexes with N2O2 donor sets as cytotoxic and antitumor agents | OAT, TNPO3, TXNRD1 | NAPRT 1394/4885TSHR 1988/4885TDP1 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.