Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TEC | P42680 | 1/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12617973 | 0.84 | NQO1 (0.52) | NQO1CYSLTR1GHSRMAOBCYP3A4 | |
| SCHEMBL21865252 | 0.83 | ALOX5 (0.59) | NQO1MAOBCYP3A4ALOX5NPC1 | |
| SCHEMBL15047212 | 0.75 | NQO1 (0.58) | NQO1TSHRSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17442633 | 0.75 | NQO1 (0.54) | NQO1TSHRCYSLTR1TEC | |
| SCHEMBL17442652 | 0.75 | NQO1 (0.54) | NQO1TSHRCYP3A4TEC | |
| SCHEMBL16881222 | 0.75 | NQO1 (0.54) | NQO1TSHRTEC | |
| SCHEMBL25401591 | 0.74 | NQO1 (0.49) | NQO1TSHR | |
| SCHEMBL7648436 | 0.72 | TSHR (0.62) | TSHRCYSLTR1CYP3A4ALOX5RAB9A | |
| SCHEMBL138949 | 0.70 | NQO1 (0.59) | NQO1MIF | |
| SCHEMBL4304834 | 0.70 | NQO1 (0.51) | NQO1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745365-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| EP-3312292-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2019-09-25 | — | — | EP | disclosed |
| EP-1885875-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2019-05-22 | — | — | EP | disclosed |
| US-20190031629-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2019-01-31 | — | — | US | disclosed |
| US-10077244-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2018-09-18 | — | — | US | disclosed |
| EP-3312292-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | Promega Corporation (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-2778234-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2017-09-27 | — | — | EP | disclosed |
| US-20160176830-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-06-23 | — | — | US | disclosed |
| EP-2277872-B1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORP (US) | 2016-03-23 | — | — | EP | disclosed |
| EP-2272973-B1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORP (US) | 2015-05-27 | — | — | EP | disclosed |
| US-8476450-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2013-07-02 | — | — | US | disclosed |
| US-7951550-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2011-05-31 | — | — | US | disclosed |
| EP-2277872-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2272973-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-12 | — | — | EP | disclosed |
| EP-2272972-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-12 | — | — | EP | disclosed |
| US-20080299593-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2008-12-04 | — | — | US | disclosed |
| EP-1935986-A2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1885875-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2007-01-18 | — | — | US | disclosed |
| WO-2006130551-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745365-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | NQO1 91/4885TSHR 4299/4885CYSLTR1 127/4885 |
| US-10077244-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | NQO1 95/4885TSHR 4312/4885CYSLTR1 126/4885 |
| US-20080299593-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | NQO1 91/4885TSHR 4299/4885CYSLTR1 127/4885 |
| US-20190031629-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | GLB1, NOD1, PYCARD | NQO1 91/4885TSHR 4299/4885CYSLTR1 127/4885 |
| US-20160176830-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | GLB1, NOD1, PYCARD | NQO1 95/4885TSHR 4312/4885CYSLTR1 126/4885 |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | NQO1 516/4885TSHR 3767/4885CYSLTR1 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.