Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11746382 | 0.98 | GPR35 (0.61) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL11746375 | 0.85 | GPR35 (0.54) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL11684319 | 0.84 | GPR35 (0.53) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL19665842 | 0.82 | MCL1 (0.57) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL26581240 | 0.82 | PIM1 (0.45) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL6239625 | 0.80 | ALDH1A1 (0.50) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL23809216 | 0.78 | PIM1 (0.42) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL11749303 | 0.78 | PIM1 (0.52) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL14744243 | 0.77 | GPR35 (0.50) | GPR35USP2POLBHPGDALOX15 | |
| SCHEMBL5563631 | 0.77 | ALDH1A1 (0.58) | GPR35USP2POLBHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624505-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2017-04-18 | — | — | US | disclosed |
| US-9624505-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2017-04-18 | — | — | US | disclosed |
| EP-2145007-B1 | NOVEL HERBICIDE RESISTANCE GENES | DOW AGROSCIENCES LLC (US) | 2017-01-25 | — | — | EP | disclosed |
| US-20160002662-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | PIONEER HI-BRED INTERNATIONAL, INC. | 2016-01-07 | — | — | US | disclosed |
| US-20160002662-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | PIONEER HI-BRED INTERNATIONAL, INC. | 2016-01-07 | — | — | US | disclosed |
| US-9062284-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2015-06-23 | — | — | US | disclosed |
| US-9062284-B2 | Uses and detection of herbicide resistance genes for resistance to aryloxyalkanoate herbicides | DOW AGROSCIENCES LLC (US) | 2015-06-23 | — | — | US | disclosed |
| US-8884017-B2 | 2-heteroarylcarboxylic acid amides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-11-11 | — | — | US | disclosed |
| US-20130040815-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-02-14 | — | — | US | disclosed |
| US-20130040815-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2013-02-14 | — | — | US | disclosed |
| EP-1461335-B1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| EP-1320523-B1 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20050119325-A1 | N-(1-azabicyclo[2.2.2]oct-3-yl)-heteroaryl carboxamides; alpha 7-nicotinic acetylcholine receptors (nAChR) agonists; improving perception, concentration, learning and memory; neuropathic pain; acute and chronic pain | FMR LLC | 2005-06-02 | — | — | US | disclosed |
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | WARNER-LAMBERT COMPANY LLC | 2005-01-06 | — | — | US | disclosed |
| EP-1461335-A1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | Bayer HealthCare AG (DE) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003055878-A1 | 2-HETEROARYLCARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2003-07-10 | — | — | WO | disclosed |
| EP-1320523-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Warner-Lambert Company LLC (US) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002024672-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER-LAMBERT COMPANY LLC (US) | 2002-03-28 | — | — | WO | disclosed |
| US-4009994-A | Process and product of optical brightening with quaternized benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1977-03-01 | — | — | US | disclosed |
| US-3940417-A | Quaternised benzofuranyl-benzimidazoles | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | BCAT1, BCAT2, ABAT | GPR35 1773/4885USP2 1960/4885POLB 555/4885 |
| US-20130040815-A1 | USES AND DETECTION OF HERBICIDE RESISTANCE GENES FOR RESISTANCE TO ARYLOXYALKANOATE HERBICIDES | AADAC, AGXT, HPD | GPR35 4060/4885USP2 348/4885POLB 2704/4885 |
| US-20050119325-A1 | N-(1-azabicyclo[2.2.2]oct-3-yl)-heteroaryl carboxamides; alpha 7-nicotinic acetylcholine receptors (nAChR) agonists; improving perception, concentration, learning and memory; neuropathic pain; acute and chronic pain | CHRNA2, CHRNA7, CHRNA3 | GPR35 276/4885USP2 3066/4885POLB 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.