Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.58 |
| ▸ | FLT4 | P35916 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | CA9 | Q16790 | 6/20 | 0.57 |
| ▸ | CA12 | O43570 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | WDR5 | P61964 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285851 | 1.00 | FLT1 (0.58) | FLT1FLT4KDRCA1CA2 | |
| SCHEMBL9486495 | 0.91 | CA12 (0.66) | FLT1FLT4KDRCA1CA2 | |
| SCHEMBL9529388 | 0.86 | LMNA (0.63) | FLT1FLT4KDRCA1CA2 | |
| SCHEMBL5186566 | 0.86 | LMNA (0.72) | FLT1FLT4KDRCA1CA2 | |
| SCHEMBL7276663 | 0.86 | LMNA (0.63) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL6323926 | 0.85 | LMNA (0.76) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL5184835 | 0.84 | IDO1 (0.61) | CA1CA2CA9CA12MEN1 | |
| Ly-181984 SCHEMBL4612056 | 0.84 | RECQL (0.74) | CA1CA2CA9CA12MEN1 | |
| SCHEMBL9486165 | 0.84 | TP53 (0.74) | FLT1FLT4KDRCA1CA2 | |
| SCHEMBL9487468 | 0.84 | TP53 (0.74) | FLT1FLT4KDRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565429-A | HUMAN LEUCOCYTE ELASTASE INHIBITORS; EMPHYSEMA; ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | ADIR ET COMPAGNIE (FR) | 1996-10-15 | — | — | US | disclosed |