Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.49 |
| ▸ | MME | P08473 | 6/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069293 | 0.85 | ALDH1A1 (0.56) | ACEMME | |
| SCHEMBL9069245 | 0.83 | NAALAD2 (0.51) | ACEMME | |
| SCHEMBL7438876 | 0.81 | ACE (0.44) | ACEMME | |
| SCHEMBL7438882 | 0.81 | ACE (0.44) | ACEMME | |
| SCHEMBL9068558 | 0.81 | LMNA (0.45) | ACEMME | |
| SCHEMBL11272524 | 0.80 | ACE (0.43) | ACEMME | |
| SCHEMBL16314051 | 0.80 | MME (0.56) | ACEMMETGFBR1 | |
| SCHEMBL7433763 | 0.79 | ACE (0.43) | ACEMME | |
| SCHEMBL7433759 | 0.79 | ACE (0.43) | ACEMME | |
| SCHEMBL9069033 | 0.78 | MME (0.63) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |