Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 8/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433763 | 1.00 | ACE (0.43) | ACEMMENAALAD2FOLH1SLC1A1 | |
| SCHEMBL9069245 | 0.87 | NAALAD2 (0.51) | ACEMMENAALAD2FOLH1RIMKLA | |
| SCHEMBL7438876 | 0.86 | ACE (0.44) | ACEMME | |
| SCHEMBL7438882 | 0.86 | ACE (0.44) | ACEMME | |
| SCHEMBL11272524 | 0.84 | ACE (0.43) | ACEMMENAALAD2FOLH1 | |
| SCHEMBL9068558 | 0.80 | LMNA (0.45) | ACEMMEFOLH1 | |
| SCHEMBL9069230 | 0.79 | ACE (0.49) | ACEMME | |
| SCHEMBL9069293 | 0.78 | ALDH1A1 (0.56) | ACEMMENAALAD2FOLH1 | |
| SCHEMBL14081153 | 0.76 | NOD1 (0.53) | ACEMMENAALAD2FOLH1SLC1A1 | |
| SCHEMBL4577285 | 0.75 | MAPT (0.52) | NAALAD2FOLH1SLC1A1RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | claimed |
| EP-0384636-A1 | Pharmaceutically active compounds | FISONS plc (GB) | 1990-08-29 | — | — | EP | disclosed |