Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 6/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.43 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067765 | 0.89 | ALDH1A1 (0.54) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL9069230 | 0.85 | ACE (0.49) | MMEACE | |
| SCHEMBL9069245 | 0.81 | NAALAD2 (0.51) | MMEACEFOLH1NAALAD2 | |
| SCHEMBL7413931 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL15223612 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MEN1LMNAKMT2AMME | |
| SCHEMBL7438876 | 0.80 | ACE (0.44) | MMEACE | |
| SCHEMBL9068558 | 0.80 | LMNA (0.45) | ALDH1A1LMNAMMEACEFOLH1 | |
| SCHEMBL7438882 | 0.80 | ACE (0.44) | MMEACE | |
| SCHEMBL11272524 | 0.79 | ACE (0.43) | KMT2AMMEACEFOLH1NAALAD2 | |
| SCHEMBL11563990 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MEN1LMNAKMT2AMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |