Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MME | P08473 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069293 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL11440933 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL11563990 | 0.86 | ALDH1A1 (0.46) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL9068534 | 0.86 | ACE (0.43) | ALDH1A1MME | |
| SCHEMBL10920363 | 0.86 | ACE (0.43) | ALDH1A1MME | |
| SCHEMBL11321753 | 0.85 | CPB2 (0.55) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL10916226 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MMEMEN1LMNAKMT2A | |
| SCHEMBL11124818 | 0.83 | MME (0.70) | MMEMMP2MMP9MMP7MMP12 | |
| SCHEMBL7324192 | 0.83 | MME (0.70) | MMEMMP2MMP9MMP7MMP12 | |
| SCHEMBL9068808 | 0.83 | MMP2 (0.65) | MMEMMP2MMP9MMP7MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5496805-A | DIURETIC, HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1996-03-05 | — | — | US | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |