Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1557480 | 0.87 | ADRA1A (0.53) | PLA2G2AADRA1APLA2G4ALMNAEPHX2 | |
| SCHEMBL4120700 | 0.85 | ADRA1A (0.62) | PLA2G2AADRA1APLA2G4ALMNAEPHX2 | |
| SCHEMBL15535068 | 0.84 | ALDH1A1 (0.41) | PLA2G2AADRA1ATGFBR1LMNASLC15A2 | |
| SCHEMBL907297 | 0.84 | ADRA1A (0.66) | PLA2G2AADRA1APLA2G4ALMNAKDM4E | |
| SCHEMBL1333097 | 0.84 | ADRA1A (0.66) | PLA2G2AADRA1APLA2G4ALMNAKDM4E | |
| SCHEMBL907518 | 0.84 | ADRA1A (0.66) | PLA2G2AADRA1APLA2G4ALMNAKDM4E | |
| SCHEMBL21099597 | 0.84 | ADRA1A (0.66) | PLA2G2AADRA1APLA2G4ALMNAKDM4E | |
| SCHEMBL18884967 | 0.84 | ADRA1A (0.50) | PLA2G2AADRA1APLA2G4ALMNAEPHX2 | |
| SCHEMBL1173562 | 0.84 | ADRA1A (0.66) | PLA2G2AADRA1APLA2G4ALMNAKDM4E | |
| SCHEMBL1332492 | 0.84 | ADRA1A (0.66) | PLA2G2AADRA1APLA2G4ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999908-B2 | Method for making photochromic contact lenses | ALCON INC. (CH) | 2024-06-04 | — | — | US | claimed |
| US-20230364832-A1 | METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES | ALCON INC. (CH) | 2023-11-16 | — | — | US | claimed |
| WO-2023209630-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| WO-2023209631-A1 | METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | WO | claimed |
| US-20230350100-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-02 | — | — | US | claimed |
| EP-4158392-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | Alcon Inc. (CH) | 2023-04-05 | — | — | EP | claimed |
| US-20220403127-A1 | MIXED-CHARGE COPOLYMER ANTIBIOFILM COATINGS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-12-22 | — | — | US | claimed |
| US-20210371731-A1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC. (CH) | 2021-12-02 | — | — | US | claimed |
| WO-2021141545-A1 | MIXED-CHARGE COPOLYMER ANTIBIOFILM COATINGS | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2021-07-15 | — | — | WO | claimed |
| US-10166527-B2 | Surface modification of porous base supports | MERCK PATENT GMBH (DE) | 2019-01-01 | — | — | US | claimed |
| US-20110136925-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-09 | — | — | US | claimed |
| EP-2310104-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | Merck Patent GmbH (DE) | 2011-04-20 | — | — | EP | claimed |
| WO-2010012358-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | WO | claimed |
| US-20090131551-A1 | POLYFUNCTIONAL COMPOUNDS AND USES AS IMPLANT MATERIALS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-05-21 | — | — | US | claimed |
| WO-2007103665-A2 | POLYFUNCTIONAL COMPOUNDS AND USES AS IMPLANT MATERIALS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2007-09-13 | — | — | WO | claimed |
| US-20050165136-A1 | Glass-ionomer cements containing amino acids | UAB RESEARCH FOUNDATION (US) | 2005-07-28 | — | — | US | claimed |
| EP-1503717-A1 | GLASS-IONOMER CEMENTS CONTAINING AMINO ACIDS | The UAB Research Foundation (US) | 2005-02-09 | — | — | EP | claimed |
| US-20040156795-A1 | Dental self-etching primer | NIHON UNIVERSITY, SCHOOL JURIDICAL PERSON (JP) | 2004-08-12 | — | — | US | claimed |
| EP-1421927-A1 | DENTAL SELF-ETCHING PRIMER | Nihon University, School Juridical Person (JP) | 2004-05-26 | — | — | EP | claimed |
| WO-2003061606-A1 | GLASS-IONOMER CEMENTS CONTAINING AMINO ACIDS | UAB RESEARCH FOUNDATION (US) | 2003-07-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131551-A1 | POLYFUNCTIONAL COMPOUNDS AND USES AS IMPLANT MATERIALS | ECPAS, PAM, INTS9 | PLA2G2A 2321/4885ECE1 3652/4885ADRA1A 4751/4885 |
| US-20040156795-A1 | Dental self-etching primer | GABARAP, GABRE, GABRA6 | PLA2G2A 1017/4885ECE1 2385/4885ADRA1A 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.