Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632690 | 0.78 | ACE (0.43) | ACE | |
| SCHEMBL8632689 | 0.78 | ACE (0.43) | ACE | |
| SCHEMBL8632684 | 0.78 | ACE (0.43) | ACE | |
| SCHEMBL6167536 | 0.77 | ACE (0.36) | ACEPREPPOLBL3MBTL1 | |
| SCHEMBL6167538 | 0.77 | ACE (0.36) | ACEPREPPOLBL3MBTL1 | |
| SCHEMBL21696767 | 0.73 | ALDH1A1 (0.48) | PREP | |
| SCHEMBL27844506 | 0.72 | HPGD (0.44) | — | |
| SCHEMBL18193416 | 0.70 | MEN1 (0.35) | L3MBTL1 | |
| SCHEMBL27825436 | 0.69 | CHRNB2 (0.46) | L3MBTL1 | |
| SCHEMBL8636076 | 0.68 | FKBP1A (0.49) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2511605-B2 | — | — | 1996-07-03 | — | — | JP | claimed |
| EP-0536163-A1 | AROMATIC PYRROLIDINE AND THIAZOLIDINE AMIDES | PFIZER INC. (US) | 1993-04-14 | — | — | EP | claimed |
| WO-1991018891-A1 | AROMATIC PYRROLIDINE AND THIAZOLIDINE AMIDES | PFIZER INC. (US) | 1991-12-12 | — | — | WO | claimed |