Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 12/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075646 | 0.81 | SMN1; SMN2 (0.45) | HIF1AHTTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL11534363 | 0.72 | MAPT (0.66) | LMNAALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL26602375 | 0.72 | HIF1A (0.64) | HIF1AKDM4E | |
| SCHEMBL8305025 | 0.69 | ALDH1A1 (0.41) | TDP1LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14486923 | 0.68 | NOTUM (0.56) | ALDH1A1HPGDMAPT | |
| SCHEMBL11408843 | 0.68 | MAPT (0.83) | TDP1HTTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL9076806 | 0.67 | MAOB (0.42) | TDP1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL4509741 | 0.67 | MAPT (0.57) | ALDH1A1HPGDSMN1; SMN2MAPTKDM4E | |
| SCHEMBL15022422 | 0.67 | MCL1 (0.60) | ALDH1A1HPGDSMN1; SMN2MAPTKDM4E | |
| SCHEMBL9076541 | 0.67 | MAPT (0.44) | HIF1ASMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565488-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-15 | — | — | US | claimed |