Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 6/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28769711 | 0.82 | THRA (0.45) | NPSR1THRATHRBLMNA | |
| SCHEMBL1208625 | 0.79 | L3MBTL1 (0.59) | NPSR1DHFRLTB4RLTB4R2THRA | |
| SCHEMBL362209 | 0.78 | LMNA (0.59) | NPSR1LMNAFFAR1 | |
| SCHEMBL29590071 | 0.78 | LMNA (0.59) | NPSR1LMNAFFAR1 | |
| Hydrochloric Acid SCHEMBL7413528 | 0.77 | LMNA (0.57) | NPSR1LMNAFFAR1 | |
| SCHEMBL8084798 | 0.76 | LTB4R (0.62) | NPSR1DHFRLTB4RLTB4R2THRA | |
| SCHEMBL9418061 | 0.76 | NPSR1 (0.59) | NPSR1LTB4RLTB4R2THRATHRB | |
| SCHEMBL31112844 | 0.76 | NPSR1 (0.59) | NPSR1LTB4RLTB4R2THRATHRB | |
| SCHEMBL4557520 | 0.76 | NPSR1 (0.56) | NPSR1DHFRLTB4RLTB4R2THRA | |
| SCHEMBL8072582 | 0.75 | LTB4R (0.64) | NPSR1DHFRLTB4RLTB4R2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741716-A1 | DELTA 12,13 -ISO-TAXOL ANALOGS, ANTINEOPLASTIC USE AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARMACIA & UPJOHN COMPANY (US) | 1996-11-13 | — | — | EP | disclosed |