Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.34 |
| ▸ | HTR3B | O95264 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL9051552 | 0.77 | NPSR1 (0.46) | NPSR1MAPTBLMSLC6A4SPR | |
| SCHEMBL9076172 | 0.74 | HTR3A (0.55) | NPSR1MAPTSLC6A4HTR3EHTR3B | |
| Fumaric Acid SCHEMBL9051571 | 0.73 | HTR3A (0.48) | NPSR1MAPTBLMSLC6A4SPR | |
| SCHEMBL9076871 | 0.73 | RAB9A (0.38) | NPSR1MAPTALDH1A1LMNACYP2C9 | |
| Fumaric Acid SCHEMBL9052105 | 0.64 | HTR3A (0.49) | SLC6A4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9051560 | 0.64 | HTR3A (0.39) | NPSR1MAPTSLC6A4HTR3EHTR3B | |
| SCHEMBL9075220 | 0.63 | TNFSF11 (0.43) | — | |
| SCHEMBL3180338 | 0.63 | HTR3A (0.55) | SLC6A4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3180342 | 0.63 | HTR3A (0.55) | SLC6A4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9048813 | 0.62 | MEN1 (0.45) | SLC6A4HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496942-A | 5-HT3-RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5344927-A | 5-HT3 antagonist | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |